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301-00-8

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301-00-8 Usage

Chemical Properties

clear colorless liquid

Occurrence

Reported found in banana, grape, grapefruit juice, melon, strawberries, mushroom and cassava.

Uses

Methyl Linolenate has potential application towards human lung carcinoma cell lines, displaying cytotoxicity. Essential oil component.

Biochem/physiol Actions

Methyl linolenate, a polyunsaturated fattly acid (PUFA), is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. Methyl linolenate is being studied as a possible skin whitening agent with anti-melanogenesis activity.

Check Digit Verification of cas no

The CAS Registry Mumber 301-00-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,0 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 301-00:
(5*3)+(4*0)+(3*1)+(2*0)+(1*0)=18
18 % 10 = 8
So 301-00-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H32O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21-2/h4-5,7-8,10-11H,3,6,9,12-18H2,1-2H3/b5-4-,8-7-,11-10-

301-00-8 Well-known Company Product Price

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  • CAS number
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  • Detail
  • Sigma

  • (L2626)  Methyllinolenate  ≥99% (GC)

  • 301-00-8

  • L2626-100MG

  • 484.38CNY

  • Detail
  • Sigma

  • (L2626)  Methyllinolenate  ≥99% (GC)

  • 301-00-8

  • L2626-500MG

  • 842.40CNY

  • Detail
  • Sigma

  • (L2626)  Methyllinolenate  ≥99% (GC)

  • 301-00-8

  • L2626-1G

  • 1,396.98CNY

  • Detail
  • Sigma

  • (L2626)  Methyllinolenate  ≥99% (GC)

  • 301-00-8

  • L2626-5G

  • 5,315.31CNY

  • Detail
  • Sigma-Aldrich

  • (62200)  Methyllinolenate  analytical standard

  • 301-00-8

  • 62200-1ML

  • 896.22CNY

  • Detail
  • Sigma-Aldrich

  • (62200)  Methyllinolenate  analytical standard

  • 301-00-8

  • 62200-5ML

  • 3,169.53CNY

  • Detail
  • USP

  • (1430349)  Methyllinolenate  United States Pharmacopeia (USP) Reference Standard

  • 301-00-8

  • 1430349-5X50MG

  • 4,662.45CNY

  • Detail

301-00-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name METHYL LINOLENATE

1.2 Other means of identification

Product number -
Other names methyl (Z,Z,Z)-octadeca-9,12,15-trienoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:301-00-8 SDS

301-00-8Relevant articles and documents

Epoxy-acetogenins and other polyketide epoxy derivatives as inhibitors of the mitochondrial respiratory chain complex I

Tormo, Jose R.,Zafra-Polo,Serrano, Angel,Estornell, Ernesto,Cortes, Diego

, p. 318 - 323 (2000)

Annonaceous acetogenins (ACG), an extensive group of cytotoxic natural products, are antitumor agents whose main mode of action is inhibition of the mammalian mitochondrial complex I. Herein we describe the importance of the different chemical groups along the alkyl chain for optimal inhibitory potency, discussing the structurally relevant factors present in these compounds. For this purpose, a series of epoxide derivatives from α- linolenic acid were prepared and their activity compared with that of epoxy- acetogenins and tetrahydrofuranic (THF) acetogenins isolated from Rollinia membranacea.

Secondary metabolites of Astragalus danicus Retz. and A. inopinatus Boriss

Gromova,Lutsky,Cannon,Li,Owen

, p. 1107 - 1112 (2001)

The chemical composition of the above-ground parts of Astragalus danicus and A. inopinatus collected in the Baikal region (Eastern Siberia) was studied for the first time. From A. danicus, pentacyclic triterpene saponins were isolated and identified, viz., 3-O-(β-glucuronopyranosyl)-3β,22β,24-trihydroxyolean-12-ene, 3-O-[O-(β-D-xylopyranosyl)-(1→2)-(β-glucuronopyranosyl)]-3β, 22β,24-trihydroxyolean-12-ene, 3-O-[O-(β-D-glucopyranosyl)-(1→2)-(β-glucuronopyranosyl)]-3β ,22β,24-trihydroxyolean-12-ene, 3-O-[O-(α-L-rhamnopyranosyl)-(1→2)-O-(β-D-xylopyranosyl) -(1→2)-(β-glucuronopyranosyl)]-3β,22β,24-trihydroxyolean-12-ene, 3-O-[O-(α-L-rhamnopyranosyl)-(1→2)-O-(β-D-glucopyranosyl)-(l-2)-(β-glucuronopyranosyl)]-3β,22β,24-trihydroxyolean-12-ene, 3-O-methyl-D-chiro-inositol, and linolenic acid. In A. inopinatus, the same saponins were identified as well as tricosan-1-ol and tetracosan-1-ol, 5,7,4′-trihydroxyflavon (apigenin), and atetracyclic triterpenoid, 20(R),24(S)-epoxycyclolanost-9(11)-ene-3β,6α, 16β, 25-tetrol (cycloastragenol). All reported compounds from the both genus of Astragalus were isolated for the first time. Methanolic extracts of A. danicus and A. inopinatus exhibited low inhibitory activity with respect to the growth of HeLa cells. The chloroform fraction of A. danicus showed a strong antimicrobial activity against Staphylococcus aureus and a strong cytotoxic activity against HeLa cells.

Detection and identification of complex oxylipins in meadow buttercup (Ranunculus acris) leaves

Chechetkin, Ivan R.,Blufard, Alexander S.,Yarin, Andrey Y.,Fedina, Evgenia O.,Khairutdinov, Bulat I.,Grechkin, Alexander N.

, p. 92 - 102 (2018/11/06)

Screening of linolipins, i.e. galactolipids containing esterified residues of divinyl ether oxylipins, in the leaves of several higher plants revealed the presence of these complex oxylipins in the meadow buttercup leaves. The rapid accumulation of linoli

Stereoselective Synthesis of Z Fluoroalkenes through Copper-Catalyzed Hydrodefluorination of gem-Difluoroalkenes with Water

Hu, Jiefeng,Han, Xiaowei,Yuan, Yu,Shi, Zhuangzhi

supporting information, p. 13342 - 13346 (2017/10/17)

A copper catalytic system was established for the stereoselective hydrodefluorination of gem-difluoroalkenes through C?F activation to synthesize various Z fluoroalkenes. H2O is used as the hydrogen source for the fluorine acceptor moiety. This mild catalytic system shows good-functional group compatibility, accepting a range of carbonyls as precursors to the gem-difluoroalkenes, including aliphatic, aromatic, and α,β-unsaturated aldehydes and even ketones. It serves as a powerful synthetic method for the late-stage modification of complex compounds.

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