30193-57-8

Basic information

• Product Name: (2S,3S)-3-(2-AMINO-PHENYLSULFANYL)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID
• Synonyms: (2S,3S)-3-(2-AMINO-PHENYLSULFANYL)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID
• CAS NO: 30193-57-8
• Molecular Formula: C₁₆H₁₇NO₄S
• Molecular Weight: 319.37548
• Mol File: 30193-57-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2S,3S)-3-(2-AMINO-PHENYLSULFANYL)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-(2-AMINO-PHENYLSULFANYL)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID(30193-57-8)
• EPA Substance Registry System: (2S,3S)-3-(2-AMINO-PHENYLSULFANYL)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID(30193-57-8)

Safety Data

• Hazardous Substances Data: 30193-57-8(Hazardous Substances Data)

Usage

General Description

The chemical "(2S,3S)-3-(2-amino-phenylsulfanyl)-2-hydroxy-3-(4-methoxy-phenyl)-propionic acid" is a compound with a molecular structure containing an amino group, a hydroxy group, and a phenylsulfanyl group. It is a derivative of 2-hydroxy-3-(4-methoxy-phenyl)-propionic acid and is classified as a chiral molecule, meaning it has two different optical isomers. (2S,3S)-3-(2-AMINO-PHENYLSULFANYL)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID may have potential applications in pharmaceuticals, as it may exhibit biological activity due to its structural features. Further research and testing are necessary to better understand the properties and potential uses of this chemical compound.

Upstream product

• 137-07-5 2-amino-benzenethiol 
• 96125-49-4 methyl trans-3-(4-methoxyphenyl)glycidate 
• 30193-56-7 (2RS,3RS)-3-(2'-aminophenylthio)-2-hydroxy-3-(4''-methoxyphenyl)-propionic acid methyl ester 
• 16546-01-3 ethyl 3-(4-methoxyphenyl)-2,3-epoxypropionate 
• 30067-00-6 methyl 2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)propionate 
• 30193-47-6 3-(2-Amino-phenylsulfanyl)-2-hydroxy-3-(4-methoxy-phenyl)-propionic acid ethyl ester 

Downstream Products

• 42399-51-9 cis-(+)-2-(4'-methoxyphenyl)-3-hydroxy-2,3-dihydro-1,5-benzothiazepine-4(5H)-one 
• 42399-48-4 (2S,3S)-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propionic acid 
• 27068-88-8 (+/-)-trans-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 
• 27068-88-8 3c-hydroxy-2r-(4-methoxy-phenyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 
• 27068-88-8 2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 

Relevant articles and documents

Carbohydrates as Chiral Auxiliaries in Asymmetric Darzens Reactions: Enantioselective Synthesis of the Benzothiazepine Ring System of Diltiazem

Carbohydrate alcohols 11 and 14, prepared from D-glucose and D-galactose, are employed as their chloro acetes 18 and 19 in the asymmetric Darzens glycidic ester condensation with p-anisaldehyde.Alcohol 11 induces modest diastereoselectivity (65:35) and af

Novel optically active carboxylic acid derivative l-lysine salt and process for production thereof

A novel salt of d-threo-2-hydroxy-3-(2-amino--phenylthio)-3-(4-methoxyphenyl)-propionic acid represented by the following formula (1) wherein C* represents the carbon atoms of the optically resolved molecules,with L-lysine. The above compound can be produced by reacting d1-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4--methoxyphenyl)-propionic acid with L-lysine or a metal salt of said propionic acid with an acid salt of L-lysine to form corresponding salts, and separating the difficult-ly-soluble salt from the resulting two optically active salts by utilizing the difference in solubility in a solvent between the two optically active salts. This compound is useful as a synthesis intermediate for a known pharmaceutical compound, diltiazem hydrochloride.

Process for preparing 1,5-benzothiazephine derivatives

A process for preparing 1,5-benzothiazepine derivatives of the formula: STR1 wherein Ar is a phenyl substituted with a lower alkoxy, R is a lower alkyl, R1 and R2 are each a lower alkyl, and Y is a lower alkylene, which have excellent coronary vasodilating and psychoneurotic activities and are useful particularly as a Ca++ -antagonistic coronary vasodilator.