30861-27-9

Basic information

• Product Name: ALOESIN
• Synonyms: ALOESIN;4H-1-Benzopyran-4-one, 8-.beta.-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-;2-(2-Oxopropyl)-5-methyl-7-hydroxy-8-(β-D-glucopyranosyl)-4H-1-benzopyran-4-one;8-β-D-Glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one;Aloe resin B;Aloeresin B;Aloeresin
• CAS NO: 30861-27-9
• Molecular Formula: C₁₉H₂₂O₉
• Molecular Weight: 394.374
• Product Categories: Carbohydrates & Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 30861-27-9.mol

Chemical Properties

• Boiling Point: 628°Cat760mmHg
• Flash Point: 224.2°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 1.22E-16mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.58±0.40(Predicted)
• CAS DataBase Reference: ALOESIN(CAS DataBase Reference)
• NIST Chemistry Reference: ALOESIN(30861-27-9)
• EPA Substance Registry System: ALOESIN(30861-27-9)

Safety Data

• Hazardous Substances Data: 30861-27-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
ALOESIN is used as a therapeutic agent for managing pre-diabetic states, particularly metabolic syndrome. Its presence in Aloe species contributes to the plant's medicinal properties, making it a valuable component in the development of treatments for diabetes and related conditions.
Used in Nutraceutical Industry:
ALOESIN is used as an ingredient in health supplements and functional foods due to its potential benefits in managing pre-diabetic states and promoting overall health. Its inclusion in these products can help support metabolic health and contribute to a balanced diet for individuals at risk of developing diabetes or metabolic syndrome.

InChI:InChI=1/C19H22O9/c1-7-3-10(22)14(19-17(26)16(25)15(24)12(6-20)28-19)18-13(7)11(23)5-9(27-18)4-8(2)21/h3,5,12,15-17,19-20,22,24-26H,4,6H2,1-2H3/t12-,15-,16+,17-,19-/m1/s1

Upstream product

• 74545-79-2 aloeresin A 

Downstream Products

• 74545-79-2 aloeresin A 

Relevant articles and documents

2'-p-METHOXYCOUMAROYLALOERESIN, A C-GLUCOSIDE FROM ALOE EXCELSA

The leaves of Aloe excelsa afforded, aloesin, anthraquinones and a new compound 2'-p-methoxycoumaroylaloeresin whose structure, 2-acetonyl-7-hydroxy-8-C-β-D--methylchromone, was established by spectral and chemical means. - Key Word Index: Aleo excelsa; Liliaceae; aloesin; C-glucosides; p-methoxycoumaroylaloeresin.

METHOD FOR CONVERTING ALOERESIN A TO ALOESIN

The invention provides a process for hydrolytically converting aloeresin A to aloesin by the following reaction: The amount of aloesin available for extraction from sap of aloe plants is thereby increased and the extraction and purification of the aloesin is also made easier and less costly. As aloesin is more commercially valuable than aloeresin A, the process also increases the commercial value of the sap or aloe bitters from the aloe plant. The process optionally also includes the step of separating the aloesin from the p-coumaric acid. Typical hydrolysis steps that are used in the process are acid hydrolysis, base hydrolysis and enzymatic hydrolysis. In the case of acid hydrolysis, the acid is any suitable organic or inorganic acid, such as hydrochloric acid, sulfuric acid, nitric acid or phosphoric acid. In the case of enzymatic hydrolysis, the hydrolytic enzyme is typically an esterase, a lipase or a protease.