3116-35-6

Basic information

• Product Name: 1-(piperazin-1-yl)-2-propylpentan-1-one
• Synonyms: 1-(piperazin-1-yl)-2-propylpentan-1-one;1-Pentanone, 1-(1-piperazinyl)-2-propyl-
• CAS NO: 3116-35-6
• Molecular Formula: C₁₂H₂₄N₂O
• Molecular Weight: 212.3318
• Mol File: 3116-35-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 339.8°C at 760 mmHg
• Flash Point: 159.3°C
• Density: 0.946g/cm³
• Vapor Pressure: 8.99E-05mmHg at 25°C
• Refractive Index: 1.467
• CAS DataBase Reference: 1-(piperazin-1-yl)-2-propylpentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(piperazin-1-yl)-2-propylpentan-1-one(3116-35-6)
• EPA Substance Registry System: 1-(piperazin-1-yl)-2-propylpentan-1-one(3116-35-6)

Safety Data

• Hazardous Substances Data: 3116-35-6(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 1069-66-5 sodium valproate 

Relevant articles and documents

Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis

8-Nitrobenzothiazinones (BTZs) are a promising class of antimycobacterial agents currently under investigation in clinical trials. Starting from thiourea derivatives, a new synthetic pathway to BTZs was established. It allows the formation of the thiazinone ring system in one synthetic step and is applicable for preparation of a wide variety of BTZ analogues. The synthetic procedure furthermore facilitates the replacement of the sulphur atom in the thiazinone ring system by oxygen or nitrogen to afford the analogous benzoxazinone and quinazolinone systems. 36 BTZ analogues were prepared and tested in luminescence-based assays for in vitro activity against Mycobacterium tuberculosis (Mtb) using the microdilution broth method and a high-throughput macrophage infection assay.