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Polyinosinic-polycytidylic acid potassium salt, also known as Poly(I) ? Poly(C), is a double-stranded homopolymer that mimics double-stranded RNA. It is recognized by toll-like receptor-3 (TLR3) and serves as a model compound to study cell signaling and immune responses against viral pathogens.

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  • China Biggest Factory Manufacturer Supply POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT CAS 31852-29-6

    Cas No: 31852-29-6

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  • 31852-29-6 Structure
  • Basic information

    1. Product Name: POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT
    2. Synonyms: POLY[I] POLY[C] POTASSIUM SALT;POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT;Polyinosinic acid . Polycytidylic acid potassium salt;polyinosinic-polycytidylic acid*potassium;polyinosinic acid/ polycytidylic potassium;Poly I:C PotassiuM Salt;5'-Cytidylic acid homopolymer complex with 5'-inosinic acid homopolyme potassium salt;5'-Cytidylic acid polymers complex with 5'-inosinic acid polymers potassium salt
    3. CAS NO:31852-29-6
    4. Molecular Formula: C19H27KN7O16P2 *
    5. Molecular Weight: 710.500802
    6. EINECS: N/A
    7. Product Categories: Biochemicals and Reagents;Biomaterials;Cell Culture;Materials Science;Nucleosides;Nucleotides;Oligonucleotide Polymers and Copolymers;Oligonucleotides;Other adjuvants;Synthetic Oligonucleotides and Related Reagents;Vaccine Adjuvants;Vaccine Production
    8. Mol File: 31852-29-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT(CAS DataBase Reference)
    10. NIST Chemistry Reference: POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT(31852-29-6)
    11. EPA Substance Registry System: POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT(31852-29-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 31852-29-6(Hazardous Substances Data)

31852-29-6 Usage

Uses

Used in Immunotherapy:
Polyinosinic-polycytidylic acid potassium salt is used as an immune response modulator for enhancing the body's natural defense mechanisms against viral infections. It activates TLR3, a TRIF-dependent receptor, which in turn triggers a cascade of immune responses to combat viral pathogens.
Used in Cancer Therapy:
Polyinosinic-polycytidylic acid potassium salt is used as an apoptosis inducer in cancer treatment. It has the potential to trigger programmed cell death in certain cancer cells, thereby contributing to the reduction of tumor growth and progression.
Used in Pharmaceutical Research:
Polyinosinic-polycytidylic acid potassium salt is utilized as a model compound in the development and testing of new drugs targeting TLR3 and related immune pathways. This helps in understanding the mechanisms of action and potential therapeutic applications in various diseases, including viral infections and cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 31852-29-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,8,5 and 2 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 31852-29:
(7*3)+(6*1)+(5*8)+(4*5)+(3*2)+(2*2)+(1*9)=106
106 % 10 = 6
So 31852-29-6 is a valid CAS Registry Number.

31852-29-6 Well-known Company Product Price

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  • Sigma

  • (P9582)  Polyinosinic–polycytidylic acid potassium salt  with buffer salts, TLR ligand tested

  • 31852-29-6

  • P9582-5MG

  • 1,097.46CNY

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  • Sigma

  • (P9582)  Polyinosinic–polycytidylic acid potassium salt  with buffer salts, TLR ligand tested

  • 31852-29-6

  • P9582-50MG

  • 5,528.25CNY

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