320407-92-9

Basic information

• Product Name: 4-BROMOMETHYL-2-CHLORO-1-METHOXYBENZENE
• Synonyms: 4-BROMOMETHYL-2-CHLORO-1-METHOXYBENZENE;3-Chloro-4-Methoxybenzyl broMide;-2-chloro-1-methoxybenzene
• CAS NO: 320407-92-9
• Molecular Formula: C₈H₈BrClO
• Molecular Weight: 235.51
• Product Categories: pharmacetical
• Mol File: 320407-92-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 272.95°C at 760 mmHg
• Flash Point: 118.876°C
• Appearance: /
• Density: 1.521g/cm³
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.565
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-BROMOMETHYL-2-CHLORO-1-METHOXYBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMOMETHYL-2-CHLORO-1-METHOXYBENZENE(320407-92-9)
• EPA Substance Registry System: 4-BROMOMETHYL-2-CHLORO-1-METHOXYBENZENE(320407-92-9)

Safety Data

• Hazardous Substances Data: 320407-92-9(Hazardous Substances Data)

Usage

General Description

4-BROMOMETHYL-2-CHLORO-1-METHOXYBENZENE is a chemical compound with the molecular formula C8H8BrClO. It is a white crystalline solid that is used in the synthesis of various pharmaceuticals and agrochemicals. 4-BROMOMETHYL-2-CHLORO-1-METHOXYBENZENE is known for its potential as an intermediate in the production of many other chemicals and is used in organic synthesis processes. It is important to handle this compound with care as it is toxic and may cause irritation to the skin, eyes, and respiratory system. Additionally, it should be stored in a cool, dry place away from sources of heat and ignition.

InChI:InChI=1/C8H8BrClO/c1-11-8-3-2-6(5-9)4-7(8)10/h2-4H,5H2,1H3

Upstream product

• 4903-09-7 3-chloro-4-methoxy-benzaldehyde 
• 22002-44-4 2-chloro-1-methoxy-4-methylbenzene 
• 613233-75-3 p-(methylthio)phenethyl bromide 
• 109418-69-1 C₈H₈ClO⁽¹⁺⁾ 
• 14425-64-0 4-methoxyphenethyl bromide 
• 14503-45-8 3-chloro-4-methoxybenzyl alcohol 

Downstream Products

• 871708-06-4 6-[(3-chloro-4-methoxyphenyl)methoxy]-1H-indazol-3-amine 
• 330784-47-9 avanafil 
• 63550-21-0 3-chloro-4-methoxy-benzenemethanethiol 

Relevant articles and documents

CHEMICAL COMPOUNDS

The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein X, Ar1, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES

The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for

Indole derivatives as MCP-1 receptor antagonists

A compound of Formula I, wherein: R1 is hydrogen, halo, methyl, ethyl or methoxy; R2 is hydrogen, halo, methyl, ethyl or methoxy; R3 is a halo group, lower alkyl, lower alkenyl, lower alkynyl, alkoxy, trifluoromethyl, nitro, cyano, trifluoromethoxy, C(O)R7, or S(O)nR7 where n is 0, 1 or 2 and R7 is an alkyl group; R4 is a halo, trifluoromethyl, methylthio, methoxy, trifluoromethoxy or lower alkyl, lower alkenyl or lower alkynyl or COR8 where R8 is lower alkyl; R6 is hydrogen, halo, lower alkyl, lower alkenyl, lower alkynyl or COR9 where R9 is lower alkyl; provided that when R1 is hydrogen, halo or methoxy, R2 is hydrogen, halo, methyl, ethyl or methoxy, R5 and R6 are both hydrogen, and one of R3 or R4 is not halo or trifluoromethyl; or a pharmaceutically acceptable salt or prodrug thereof. These compounds have useful activity for the treatment of inflammatory disease, specifically in antagonizing an MCP-1 mediated effect in a warm-blooded animal such as a human being.