325740-59-8

Basic information

• Product Name: D-erythro-Pentaric acid, 2,3-dideoxy-2-(1-methylethyl)-, 1,4-lactone (9CI)
• Synonyms: D-erythro-Pentaric acid, 2,3-dideoxy-2-(1-methylethyl)-, 1,4-lactone (9CI)
• CAS NO: 325740-59-8
• Molecular Formula: C8H12O4
• Molecular Weight: 172.17848
• Product Categories: ISOPROPYL
• Mol File: 325740-59-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: D-erythro-Pentaric acid, 2,3-dideoxy-2-(1-methylethyl)-, 1,4-lactone (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: D-erythro-Pentaric acid, 2,3-dideoxy-2-(1-methylethyl)-, 1,4-lactone (9CI)(325740-59-8)
• EPA Substance Registry System: D-erythro-Pentaric acid, 2,3-dideoxy-2-(1-methylethyl)-, 1,4-lactone (9CI)(325740-59-8)

Safety Data

• Hazardous Substances Data: 325740-59-8(Hazardous Substances Data)

Upstream product

• 1165874-77-0 (2S,4S)-tetrahydro-4-isopropyl-5-oxofuran-2-carbonitrile 
• 325740-56-5 (S)-4-Isopropyl-5-oxo-tetrahydro-furan-2-carbonyl chloride 
• 325740-55-4 (S)-5-Hydroxymethyl-3-isopropyl-dihydro-furan-2-one 
• 240821-65-2 (4S)-3-[(2S)-2-(1-methylethyl)-1-oxopent-4-en-1-yl]-4-(phenylmethyl)oxazolidin-2-one 
• 191152-26-8 (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-isopropyl-dihydro-furan-2-one 
• 145589-03-3 (S)-4-benzyl-3-(3-methylbutanoyl)oxazolidin-2-one 
• 325740-58-7 (2S,4S)-4-Isopropyl-5-oxo-tetrahydro-furan-2-carboxylic acid benzyl ester 
• 191152-27-9 (3S,5S)-5-Hydroxymethyl-3-isopropyl-dihydro-furan-2-one 

Downstream Products

• 325740-64-5 (3S,5S)-3-Isopropyl-5-{(S)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentanoyl}-dihydro-furan-2-one 
• 324763-45-3 (3S,5S)-5-{(1R,3S)-1-Hydroxy-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-3-isopropyl-dihydro-furan-2-one 
• 325740-67-8 (3S,5S)-dihydro-5-{(1S,3S)-1-hydroxy-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-3-(1-methylethyl)furan-2(3H)-one 
• 325740-70-3 (3S,5S)-5-((1S,3S)-1-azido-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one 
• 324763-46-4 (3S,5S)-5-{(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-dihydro-3-(1-methylethyl)furan-2(3H)-one 
• 325740-68-9 Methanesulfonic acid (1R,3S)-1-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl ester 
• 325740-69-0 Methanesulfonic acid (1S,3S)-1-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl ester 
• 325740-72-5 (3S,5S)-5-{(S)-1-[(Z)-Benzyloxyimino]-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-3-isopropyl-dihydro-furan-2-one 
• 325154-32-3 (2S,4S,5R,7S)-5-amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methyl-2-isopropylnonanamide 
• 173334-57-1 (2S,4S,5S,7S)-5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonanoic acid (2-carbamoyl-2-methyl-propyl)-amide 
• 325154-31-2 (2S,4S,5R,7S)-5-Azido-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonanoic acid (2-carbamoyl-2-methyl-propyl)-amide 
• 324763-47-5 (2S,4S,5S,7S)-N-(3-amino-2,2-dimethyl-3-oxopropyl)-5-azido-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(methoxypropoxy)benzyl)-8-methylnonanamide 
• 325740-60-1 tetrahydro-4-isopropyl-5-oxofuran-2-carbonyl chloride 

Relevant articles and documents

SYNTHESIS ROUTES TO 2(S),4(S),5(S),7(S)-2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES

The invention relates to a process for the preparation of compounds that are important building blocks in convergent synthesis routes to 2(S),4(S),5(S),7(S)-2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amides or pharmaceutically acceptable salts thereof, such as the compound Aliskiren, and to a process for the preparation of these octanoyl amides, comprising reacting said building block.