3260-61-5 Usage
Description
3H-indol-3-one, also known as indoxyl, is a heterocyclic compound characterized by a bicyclic structure that features a benzene ring fused to a five-membered nitrogen-containing ring. It is an indole derivative known for its diverse biological and pharmacological activities, such as antimicrobial, antioxidant, and anti-inflammatory properties. 3H-indol-3-one also serves as a precursor in the synthesis of indigo dye, a substance with a long history of use in textile dyeing across various cultures. Furthermore, 3H-indol-3-one is under investigation for its potential therapeutic applications in treating diseases like cancer and neurodegenerative disorders.
Uses
Used in Pharmaceutical Industry:
3H-indol-3-one is used as a pharmaceutical agent for its antimicrobial, antioxidant, and anti-inflammatory properties, contributing to the development of new treatments for various diseases.
Used in Cosmetic Industry:
In the cosmetic industry, 3H-indol-3-one is utilized for its beneficial properties, which may include antioxidant and anti-inflammatory effects, to improve skin health and provide protective effects against environmental stressors.
Used in Textile Industry:
3H-indol-3-one is used as a precursor in the synthesis of indigo dye, which is a significant component in the textile industry for creating vibrant blue colors in fabrics, maintaining its historical importance in textile dyeing.
Used in Research and Development:
3H-indol-3-one is employed in research settings for studying its potential applications in the treatment of various diseases, including cancer and neurodegenerative disorders, as it continues to be explored for novel therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 3260-61-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,2,6 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3260-61:
(6*3)+(5*2)+(4*6)+(3*0)+(2*6)+(1*1)=65
65 % 10 = 5
So 3260-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO/c10-8-5-9-7-4-2-1-3-6(7)8/h1-4,9H,5H2
3260-61-5Relevant articles and documents
Flash vacuum pyrolysis of 2-acetyl-3-azido[1]benzothiophene
Gaywood, Alexander P.,McNab, Hamish,McNab, Lilian
, p. 228 - 237 (2020/09/09)
Flash vacuum pyrolysis (FVP) of 2-acetyl-3-azido[1]benzothiophene at 300 °C provides 3-methyl [1]benzothieno[3,2-c]isoxazole (72%). At higher temperatures, the heteroindoxyl 1,2-dihydro[1]benzo-thieno[3,2-b]pyrrol-3-one was obtained in low yield (ca. 10%). The heteroindoxyl exists as a mixture of keto and enol forms in DMSO solution. Because of the easy oxidative dimerisation of these products to indigotin (and its heteroanalogues), such reactions are excellent examples of the synthetic advantages of FVP with the monomeric products conveniently generated under vacuum in a solvent-free, air-free environment.
Methylene meldrums acid derivatives of indoxyl and their cyclization reactions under flash vacuum pyrolysis conditions
Gaywood, Alexander P.,McNab, Hamish
experimental part, p. 1361 - 1364 (2010/07/02)
Pure indoxyl can be obtained in 75% yield by flash vacuum pyrolysis (FVP) of 2′-azidoacetophenone at 650 °C. Reaction of indoxyl with methoxymethylene Meldrums acid takes place at the 1-position, and FVP of the resulting derivative provides 1-hydroxy-9H-pyrrolo[1,2-a]indol-9-one (54%). FVP of the isomeric 2-methylene compound gives pyrano[3,2-b]indol-2(5H)-one (42%). Georg Thieme Verlag Stuttgart · New York.
Reactions of Carboxylic Acids with "Phosphonium Anhydrides"
Hendrickson, James B.,Hussoin, Md. Sajjat
, p. 1144 - 1149 (2007/10/02)
General considerations are outlined for a reagent to extract oxygen from organic molecules by an equivalent of dehydration.Reagents, (R3P+)2O, 2OTf-, were created for the purpose and subjected to a preliminary study.They were found to convert carboxylic acids readily and rapidly to anhydrides, esters, amides, amidines, benzimidazoles, and cyclic aryl ketones in good yields.