3354-37-8

Basic information

• Product Name: 4-PHENYL-3H-1,2-DITHIOLE-3-THIONE
• Synonyms: 4-PHENYL-3H-1,2-DITHIOLE-3-THIONE
• CAS NO: 3354-37-8
• Molecular Formula: C₉H₆S₃
• Molecular Weight: 210.34
• Mol File: 3354-37-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 363.3°Cat760mmHg
• Flash Point: 173.5°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 3.81E-05mmHg at 25°C
• Refractive Index: 1.774
• CAS DataBase Reference: 4-PHENYL-3H-1,2-DITHIOLE-3-THIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PHENYL-3H-1,2-DITHIOLE-3-THIONE(3354-37-8)
• EPA Substance Registry System: 4-PHENYL-3H-1,2-DITHIOLE-3-THIONE(3354-37-8)

Safety Data

• Hazardous Substances Data: 3354-37-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H6S3/c10-9-8(6-11-12-9)7-4-2-1-3-5-7/h1-6H

Upstream product

• 98-82-8 Isopropylbenzene 
• 97-39-2 1,3-Di(2-tolyl)guanidine 
• 3979-14-4 tropic acid ethyl ester 
• 17838-69-6 ethyl 3-oxo-2-phenylpropanoate 
• 98-83-9 isopropenylbenzene 
• 617-94-7 1-methyl-1-phenylethyl alcohol 

Downstream Products

• 21305-56-6 3-methylthio-4-phenyl-1,2-dithiolium iodide 
• 19791-12-9 4-phenyl-[1,2]dithiol-3-one oxime 
• 21210-86-6 1,3-Bis-(triethylsilylmercapto)-2-phenyl-propen-⁽¹⁾ 
• 62538-75-4 5-phenyl-6-thioxo-6H-[1,2,3]dithiazine-3-carboxylic acid ethyl ester 
• 53870-52-3 2-cyclohexyl-4-phenyl-2H-isothiazole-5-thione 
• 52095-93-9 4-Phenyl-2-(4-methylphenyl)-5(2H)-isothiazolthion 
• 53870-55-6 4-Phenyl-2-(4-methoxyphenyl)-5(2H)-isothiazolthion 
• 53870-51-2 2-Isopropyl-4-phenyl-5(2H)-isothiazolthion 
• 37986-28-0 2,4-diphenyl-2H-isothiazole-5-thione 
• 27684-39-5 (3,5-diphenyl-3H-[1,3,4]thiadiazol-2-ylidene)-phenyl-thioacetaldehyde 
• 53870-54-5 4-Phenyl-2-(3-methylphenyl)-5(2H)-isothiazolthion 
• 53870-49-8 2-Methyl-4-phenyl-5(2H)-isothiazolthion 
• 53870-53-4 4-Phenyl-2-(2-methylphenyl)-5(2H)-isothiazolthion 
• 53870-50-1 4-Phenyl-2-(phenylmethyl)-5(2H)-isothiazolthion 

Relevant articles and documents

Synthesis and structure-activity relationships study of dithiolethiones as inducers of glutathione in the SH-SY5Y neuroblastoma cell line

Parkinson's disease is a neurodegenerative disorder that involves the degeneration of nigrostriatal dopaminergic neurons. Elevated levels of reactive oxygen species have been shown to deplete cellular levels of the ubiquitous antioxidant glutathione, lead

N2S2 tetradentate ligands for soft cationic species: preparation of new ligands of potential interest in nuclear medicine

The synthesis of N2S2 tetradentate ligands of the bis-(enaminothioester) type was carried out starting from 3-(methylthio)-3H-1,2-dithiolylium iodides and diamines.The title compounds, which are potential ligands for soft cationic species, can be obtained from 1,3-diaminopropan-2-ol and subsequently modified into the dissymmetrical succinic acid ester of the ligand and N-hydroxysuccinimide.The appendage of such a linking group on the chelating structure should allow further grafting to monoclonal antibodies in view of potential applications in nuclear medicine. 3H-1,2-dithiole-3-thione / 1,3-diaminopropan-2-ol / bis-(enaminothioester) / N2S2 tetradentate ligand / N-hydroxysuccinimidyl ester

Dithioles

The process of reacting dithiolium compounds with an hydroxy compound such as water, alcohols, etc., under basic conditons so as to substitute the hydroxy constituent into the 3 or 5 position of the thiolium ring thus replacing the positive ionic valency with a covalent bond; and to the dithiole compositions formed and uses therefor, for example as corrosion inhibitors, etc. The process can be reversed to reform the original dithiolium compounds by reacting the dithiole compound under acidic conditions. The reactions may be summarized by the following reaction: STR1