3360-41-6 Usage
Chemical Properties
colourless liquid
Uses
Different sources of media describe the Uses of 3360-41-6 differently. You can refer to the following data:
1. 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases.
2. 4-Phenyl-1-butanol was used in synthesis of NK105, a paclitaxel-incorporating micellar nanoparticle formulation.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 31, p. 2607, 1983 DOI: 10.1248/cpb.31.2607Journal of the American Chemical Society, 73, p. 124, 1951 DOI: 10.1021/ja01145a045
General Description
4-Phenyl-1-butanol is oxidized by ceric ammonium nitrate in acetonitrile to afford 2-phenyltetrahydrofuran. It undergoes cyclization in presence of phosphoric acid at high temperature to yield tetralin.
Check Digit Verification of cas no
The CAS Registry Mumber 3360-41-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,6 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3360-41:
(6*3)+(5*3)+(4*6)+(3*0)+(2*4)+(1*1)=66
66 % 10 = 6
So 3360-41-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O/c11-9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7,11H,4-5,8-9H2
3360-41-6Relevant articles and documents
Young,Trahanovsky
, p. 5060,5062 (1969)
Matteson Reaction under Flow Conditions: Iterative Homologations of Terpenes
Kuhwald, Conrad,Kirschning, Andreas
supporting information, p. 4300 - 4304 (2021/05/26)
The Matteson reaction is ideally suited for flow chemistry since it allows iterative homologation of boronate esters. The present study provides accurate data on reaction times of the individual steps of the Matteson reaction, which occurs in less than 10 s in total. The protocol allows terpenes to be (per-)homologated in a controlled manner to yield homo-, bishomo-, and trishomo-terpenols after oxidative workup. The new terpene alcohols are validated with respect to their olfactoric properties.
Redox-active ligand based Mn(i)-catalyst for hydrosilylative ester reduction
Chakraborty, Soumi,Das, Arpan,Mandal, Swadhin K.
supporting information, p. 12671 - 12674 (2021/12/04)
Herein a Mn(i) catalyst bearing a redox-active phenalenyl (PLY) based ligand is reported for the efficient hydrosilylation of esters to alcohols using the inexpensive silane source polymethylhydrosiloxane (PMHS) under mild conditions. Mechanistic investigations suggest a strong ligand-metal cooperation where a ligand-based single electron transfer (SET) process initiates the reaction through Si-H bond activation.