338389-72-3

Basic information

• Product Name: (-)-cis-2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-oxathiolane p-toluensulfonate
• Synonyms: (-)-cis-2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-oxathiolane p-toluensulfonate
• CAS NO: 338389-72-3
• Molecular Weight: 401.464
• Mol File: 338389-72-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-cis-2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-oxathiolane p-toluensulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-cis-2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-oxathiolane p-toluensulfonate(338389-72-3)
• EPA Substance Registry System: (-)-cis-2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-oxathiolane p-toluensulfonate(338389-72-3)

Safety Data

• Hazardous Substances Data: 338389-72-3(Hazardous Substances Data)

Upstream product

• 1126897-48-0 C₁₇H₁₇N₃O₅S 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 160707-69-7 lamivudine 

Relevant articles and documents

ENANTIOMERIC RESOLUTION OF 2,4-DISUBSTITUTED 1,3-OXATHIOLANE NUCLEOSIDES

Single enantionmers of compounds of formula (B), in either the cis or trans configuration, wherein R1 and R2 are as defined herein, can be separated from enantiomeric mixtures thereof by reacting the compound with an acid to produce

Enantiomeric resolution of 2-substituted 4-substituted 1,3-oxathiolanes nucleosides

Single enantionmers of compounds of formula (B), in either the cis or trans configuration, wherein R1 and R2 are as defined herein, can be separated from enantiomeric mixtures thereof by reacting the compound with an acid to produce a conglomerate salt that has the following characteristics: the IR spectrum of the salt of the racemic compound, a 1:1 mixture of (?) and (+) crystals, is identical to that of the each of the single enantiomer, andthe salt of the racemic compound has a melting point lower that that of either single enantiomer. The conglomerate salt is then separated by preferential crystallization.