33856-06-3

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 3-[2-[(4-methylphenyl)amino]-4-thiazolyl]-
• CAS NO: 33856-06-3
• Molecular Formula: C19H14N2O2S
• Molecular Weight: 334.398
• Mol File: 33856-06-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 3-[2-[(4-methylphenyl)amino]-4-thiazolyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 3-[2-[(4-methylphenyl)amino]-4-thiazolyl]-(33856-06-3)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 3-[2-[(4-methylphenyl)amino]-4-thiazolyl]-(33856-06-3)

Safety Data

• Hazardous Substances Data: 33856-06-3(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 141099-74-3 3-(2-thiocyanatoacetyl)-2H-1-benzopyran-2-one 
• 622-52-6 p-methylphenylthiourea 
• 90-02-8 salicylaldehyde 
• 2290-65-5 trimethylsilyl isothiocyanate 
• 29310-88-1 3-bromoacetylcoumarin 
• 3949-36-8 3-acetylcoumarin 

Downstream Products

• 33856-14-3 3-[5-bromo-2-(4-methyl-anilino)-thiazol-4-yl]-chromen-2-one 
• 1234707-28-8 N-[4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl]-N-p-tolyl-acetamide 

Relevant articles and documents

A two-component protocol for synthesis of 3-(2-(substituted phenylamino)thiazol-4-yl)-2H-chromen-2-ones

An efcient 2-component synthesis of a series of 3-(2-(substituted phenylamino)thiazol-4-yl)-2H-chromen-2- ones (3a-j) was achieved by the reaction of 3-(2-thiocyanatoacetyl)-2H-chromen-2-one (1) with a variety of suitably substituted anilines in 1:1 molar ratio in ethanol. The structures of the products were established by elemental analyses, and UV-vis, FTIR, 1H and 13C NMR, and mass spectroscopy. 3-(2-(4-Methylphenylamino)thiazol-4-yl)-2H-chromen- 2- one (3j) was further characterized by single crystal X-ray diffraction study. This compound, C19H14N2 OS, crystallizes in the orthorhombic space group Pna21, with Z = 4, and unit cell parameters a = 13.0785(11), b = 25.746(2), c = 4.7235(3) A, α=β=γ= 90°. TUeBITAK.

PEG-600 mediated one-pot reaction of 3-acetyl-2: H -chromen-2-one with heterylthiols and phenylthioureas using tetrabutylammonium tribromide as an efficient green reagent

A simple method for the one-pot reaction of 3-acetyl-2H-chromen-2-one with different heterylthiols and phenylthioureas under green conditions using tetrabutylammonium tribromide (TBATB) as an efficient reagent has been described. 3-Acetyl-2H-chromen-2-one

One pot synthesis of 3-[2-(arylamino)thiazol-4-yl]coumarins in a three-component synthesis and a catalyst and solvent-free synthesis on grinding

An efficient synthesis of 3-[2-(arylamino)thiazol-4-yl]coumarins in excellent yields are described. Reaction of 3-(2-bromoacetyl)coumarin with potassium thiocyanate and arylamines, in alcohol resulted in the formation of title compounds in one pot. The sa