339186-39-9 Usage
Molecular Weight
169.19 g/mol
Structure
A phenylalanine derivative with two hydroxyl groups (-OH) at the 2 and 3 positions, respectively.
Role in Neurotransmitter Synthesis
DOPA is a precursor to dopamine, norepinephrine, and epinephrine, which are important neurotransmitters in the brain and nervous system.
Role in Melanin Synthesis
DOPA is a key intermediate in the biosynthesis of melanin, the pigment responsible for the color of hair, skin, and eyes.
Treatment for Parkinson's Disease
DOPA has been used in the treatment of Parkinson's disease, as it can be converted into dopamine in the brain, which helps alleviate the symptoms of the disease.
Potential Role in Cancer Therapy
DOPA has been studied for its potential role in cancer therapy, as it has shown some ability to inhibit the growth of certain cancer cells.
Use as a Precursor for Bio-based Materials
DOPA has been studied as a precursor for the production of bio-based materials, such as biodegradable plastics and other sustainable products.
Check Digit Verification of cas no
The CAS Registry Mumber 339186-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,9,1,8 and 6 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 339186-39:
(8*3)+(7*3)+(6*9)+(5*1)+(4*8)+(3*6)+(2*3)+(1*9)=169
169 % 10 = 9
So 339186-39-9 is a valid CAS Registry Number.
339186-39-9Relevant articles and documents
Enantiomeric analysis of pharmaceutical compounds by Ion/molecule reactions
Grigorean,Lebrilla
, p. 1684 - 1691 (2007/10/03)
Protonated complexes involving cyclodextrin hosts and guest compounds that are pharmacologically important are produced in the gas phase and reacted with a gaseous amine. The guest is exchanged to produce a new protonated complex with the amine. The reaction is enantioselective and is used to develop a method for determining enantiomeric excess using only mass spectrometry. The pharmaceutical compounds include DOPA, amphetamine, ephedrine, and penicillamine. The presence of more than one reacting species is observed with DOPA and penicillamine. Molecular dynamics calculations are used to understand the nature of the interactions and the possible source of the variations in the reactivities.
