3397-65-7

Basic information

• Product Name: N-LAUROYL-L-GLUTAMIC ACID
• Synonyms: N-(1-OXODODECYL)GLUTAMICACID;N-Dodecanoyl-L-glutamic acid;N-Dodecylglutamic acid;N-Lauroylglutamic acid;(S)-2-dodecanamidopentanedioic acid;N-LAUROYL-L-GLUTAMIC ACID;L-Glutamicacid,N-(1-oxododecyl)-(9CI);N-(1-oxododecyl)-L-glutamic acid
• CAS NO: 3397-65-7
• Molecular Formula: C₁₇H₃₁NO₅
• Molecular Weight: 329.43
• EINECS: 222-261-1
• Mol File: 3397-65-7.mol
• Article Data: 15

Chemical Properties

• Melting Point: 95-96 °C
• Boiling Point: 543.6°Cat760mmHg
• Flash Point: 282.6°C
• Appearance: /
• Density: 1.081g/cm³
• Vapor Pressure: 2.95E-13mmHg at 25°C
• Refractive Index: 1.486
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Aqueous Base (Slightly), Chloroform (Slightly)
• PKA: 3.46±0.10(Predicted)
• CAS DataBase Reference: N-LAUROYL-L-GLUTAMIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-LAUROYL-L-GLUTAMIC ACID(3397-65-7)
• EPA Substance Registry System: N-LAUROYL-L-GLUTAMIC ACID(3397-65-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3397-65-7(Hazardous Substances Data)

Usage

Uses

N-Lauroyl-L-glutamic Acid is used in preparation method thereof and application in degrdation of formaldehyde.

InChI:InChI=1/C17H31NO5/c1-2-3-4-5-6-7-8-9-10-11-15(19)18-14(17(22)23)12-13-16(20)21/h14H,2-13H2,1H3,(H,18,19)(H,20,21)(H,22,23)

Upstream product

• 118429-76-8 N^α-lauryl-L-glutamic acid dibenzyl ester 
• 143-07-7 lauric acid 
• 56-86-0 L-glutamic acid 
• 142-47-2 monosodium L-glutamate 
• 112-16-3 n-dodecanoyl chloride 
• 111-82-0 methyl n-dodecanoate 
• 142-47-2 glutamic acid sodium salt 
• 113493-05-3 C₂₁H₃₉NO₅ 
• 7783-05-3 disulfuric acid 
• 2791-84-6 L-glutamic acid dibenzyl ester 4-toluenesulfonate 

Downstream Products

• 143-07-7 lauric acid 
• 56-86-0 L-glutamic acid 
• 63663-21-8 N-lauroyl-L-glutamic acid N,N'-(dibutylamide) 

Relevant articles and documents

pH-sensitive wormlike micelle and hydrogel formation by acylglutamic acid-alkylamine complex

pH-sensitive viscoelastic fluids were obtained through the formation of wormlike micelles and hydrogels. These assemblies result from the 1:1 stoichiometric complex formation of acylglutamic acid (CnGlu) with tertiary alkylamine. The pH-sensitive nature reflects a change in the charge density around the CnGlu headgroups, controlling the curvature of the molecular assemblies. The longer chainCnGlu analogues yield the hydrogel in a narrow pH region. This study proposes a unique way to obtain stimulus-responsive viscoelastic fluids by means of gemini-like amphiphiles.

Manufacturing technology for fatty acyl amino acid

The invention discloses a manufacturing technology for fatty acyl group amino acid. The invention is characterized in that fatty acid methyl ester and amino sodium are taken as raw materials, a one-step synthesis method is adopted for synthesizing N-fatty acyl amino acid sodium surfactant under the effect of a metallic oxide catalyst and the mole ratio of the raw materials fatty acid methyl ester to sodium amino acid is (1.2-1.8):(0.7-1). The raw material proportion is proper, the by-product is almost not generated, the product synthetic ratio is as high as 87% or above, the purity is high, the problems of a large amount of to-be-treated waste acid, complex operation technology, high raw material PC13 irritation, and the like, of the traditional acyl chloride process are overcome and the technology accords with the green chemical principle. The dosage of the catalyst is reasonable; the catalyst is utilized, so that the production efficiency is greatly increased in the preparation process, the production flow is shortened and the product quality is increased; the excellent product even can be directly used as a raw material in pharmacy industry.

Regulation of the chiral twist and supramolecular chirality in co-assemblies of amphiphilic L-glutamic acid with bipyridines

A series of amphiphilic L-glutamic acid derivatives with various saturated alkyl chains has been designed and their co-assembly with 4,4′-bipyridine in aqueous media has been investigated. While the individual amphiphiles formed hydrogels with water and self-assembled into fine fiber networks, the addition of 4,4′-bipyridine caused significant changes in the co-assembled nanostructures such that twisted chiral ribbons were formed. In these supramolecular systems, either fine structural changes or adjustment of the stoichiometric ratio of the two components had crucial effects on the formation of the chiral twists. Based on detailed investigations by SEM and XRD analyses, FTIR, CD, and UV/Vis spectroscopies, and molecular simulation, it is considered that a delicate synergistic balance between π-π stacking, hydrophobic, and chiral interactions is responsible for the formation of the chiral twists. An interesting sandwich structure, in which an excess of 4,4′-bipyridine is inserted into the space of primary cages constructed from the amphiphile and 4,4′-bipyridine, is proposed. Remarkably, the handedness of these chiral twists is related not only to the chiral center of the glutamic unit, but also the chain length of the alkyl tails. This work provides a deeper understanding of the formation mechanism of chiral twists, and exemplifies a feasible shortcut to the rational design of chiral structures from basic molecular structures to supramolecular systems. Twisted nanostructures: A chiral twist has been obtained through the co-assembly of single-chain L-glutamic acids with bipyridines (see picture). The sandwiching of additional 4,4′-bipyridine within the cage formed by the amphiphile and the bipyridine caused the chiral twist. The dimensions and chirality of the twist could be regulated by adjusting the alkyl chain length of the amphiphile. Copyright