3399-22-2

Basic information

• Product Name: DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE
• Synonyms: TRANS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE;4-Cyclohexanedicarboxylicacid,dimethylester,trans-1;dimethylester,trans-4-cyclohexanedicarboxylicacid;DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE;DIMETHYL TRANS-CYCLOHEXANE-1,4-DICARBO-X YLATE;Dimethyl trans-1,4-cyclohexanedicarboxylate, 99+%;Dimethyl trans-1,4-Cyclohexanediarboxylate;(1r,4r)-dimethyl cyclohexane-1,4-dicarboxylate
• CAS NO: 3399-22-2
• Molecular Formula: C₁₀H₁₆O₄
• Molecular Weight: 200.23
• Product Categories: C10 to C11;Carbonyl Compounds;Esters;Building Blocks;C10 to C11;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 3399-22-2.mol
• Article Data: 11

Chemical Properties

• Melting Point: 67-69 °C(lit.)
• Boiling Point: 263.5±0.0℃ (760 Torr)
• Flash Point: 115.4±18.8℃
• Appearance: White to faintly yellow/Crystalline Powder
• Density: 1.102±0.06 g/cm3 (20 ºC 760 Torr)
• Refractive Index: 1.4560 (589.3 nm 31℃)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• BRN: 2213375
• CAS DataBase Reference: DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE(3399-22-2)
• EPA Substance Registry System: DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE(3399-22-2)

Safety Data

• Hazard Codes: Xi
• Statements: 52/53-38
• Safety Statements: 22-24/25-61-37
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 3399-22-2(Hazardous Substances Data)

Usage

Chemical Properties

White to faintly yellow crystalline powder

Upstream product

• 619-82-9 trans-hexahydroterephthalic acid 
• 120-61-6 1,4-benzenedicarboxylic acid dimethyl ester 
• 64-19-7 acetic acid 
• 67-56-1 methanol 
• 15177-67-0 trans-4-(methoxycarbonyl)cyclohexanecarboxylic acid 
• 13170-66-6 trans-1,4-cyclohexanedicarboxylic acid dichloride 
• 94-60-0 dimethyl 1,4-cyclohexane dicarboxylate 
• 74-88-4 methyl iodide 
• 1165952-91-9 cyclohexa-1,3-diene 
• 186581-53-3 diazomethane 
• 3919-11-7 trans-Cyclohex-2-ene-1,4-dicarboxylic acid 
• 7647-01-0 hydrogenchloride 
• 79368-45-9 7-Oxobicyclo<2.2.1>heptan-1-carbonylchlorid 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 15177-67-0 trans-4-(methoxycarbonyl)cyclohexanecarboxylic acid 
• 1467-84-1 ((1R,4R)-4-aminocyclohexyl)methanol 
• 1256276-45-5 benzyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate 
• 1260885-17-3 trans-4-[4-(3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-cyclohexyl-carboxylic acid 

Relevant articles and documents

DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS

The present invention relates to novel iminosugars and their use as glucosidase inhibitors. The present inventors discovered that certain deoxynojirimycin derivatives may be effective in inhibiting glucosidases. In particular, such deoxynojirimycin derivatives may be useful for treating a disease or condition in which inhibition of glucosidase may play an important role.

Ni-Catalyzed Site-Selective Dicarboxylation of 1,3-Dienes with CO2

A site-selective catalytic incorporation of multiple CO2 molecules into 1,3-dienes en route to adipic acids is described. This protocol is characterized by its mild conditions, excellent chemo- and regioselectivity and ease of execution under CO2 (1 atm), including the use of bulk butadiene and/or isoprene feedstocks.

TRICYCLIC PYRROLOPYRIDINE COMPOUND, AND JAK INHIBITOR

To provide a novel tricyclic pyrrolopyridine compound having a JAK inhibitory activity and useful for prevention, treatment and/or improvement of particularly autoimmune diseases, inflammatory diseases and allergic diseases. A novel tricyclic pyrrolopyridine compound represented by the formula (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof: wherein the respective substituents are defined in detail in the specification, and R1 is a C1-6 alkyl group or the like, R2 is a hydrogen atom or the like, R3 is a hydrogen atom or the like, the ring A is C3-11 cycloalkane or the like, L1 is a C1-6 alkylene group or the like, and R4 is NRaRb or the like.