34259-90-0

Basic information

• Product Name: 1-benzoyl-4-nitromethyl-piperidin-4-ol
• Synonyms: 1-benzoyl-4-nitromethyl-piperidin-4-ol
• CAS NO: 34259-90-0
• Molecular Weight: 264.281
• Mol File: 34259-90-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzoyl-4-nitromethyl-piperidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzoyl-4-nitromethyl-piperidin-4-ol(34259-90-0)
• EPA Substance Registry System: 1-benzoyl-4-nitromethyl-piperidin-4-ol(34259-90-0)

Safety Data

• Hazardous Substances Data: 34259-90-0(Hazardous Substances Data)

Upstream product

• 24686-78-0 1-Benzoyl-4-piperidone 
• 75-52-5 nitromethane 

Downstream Products

• 159634-87-4 N-[(R)-[(1,2-Dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperidin]-1'-yl)carbonyl]-2-(phenylmethyloxy)ethyl]-2-[(1,1-dimethyl-ethoxy)carbonyl]amino-2-methyl-propanamide 
• 178261-41-1 1-(methylsulfonyl)spiro[indoline-3,4’-piperidine] 
• 191487-52-2 MK-677 

Relevant articles and documents

Domino Aryne Annulation via a Nucleophilic-Ene Process

1,2-Benzdiyne equivalents possess the unique property that they can react with two arynophiles through iteratively generated 1,2- and 2,3-aryne intermediates. Upon rational modification on the second leaving group of these aryne precursors, a domino aryne annulation approach was developed through a nucleophilic-ene reaction sequence. Various benzo-fused N-heterocyclic frameworks were achievable under transition metal-free conditions with a broad substrate scope.