3433-56-5Relevant articles and documents
Visible light-induced intermolecular radical addition: Facile access to γ-ketoesters from alkyl-bromocarboxylates and enamines
Hu, Bei,Chen, Haixia,Liu, Yan,Dong, Wuheng,Ren, Kai,Xie, Xiaomin,Xu, Hao,Zhang, Zhaoguo
, p. 13547 - 13550 (2015/01/09)
A highly efficient addition of alkyl α-bromocarboxylates to enamines by visible light-induced photoredox catalysis is reported. Compared with traditional methods, the reaction described here provided an alternative route for the construction of valuable γ-ketoesters in generally good yields.
A new reactivity pattern for vinyl bromides: Cine-substitution via palladium catalysed C-N coupling/Michael addition reactions
Willis, Michael C.,Chauhan, Jay,Whittingham, William G.
, p. 3094 - 3095 (2007/10/03)
Palladium catalysed C-N bond formation can be used to convert vinyl bromides to the corresponding enamines, which are reacted in situ with alkylidene malonates to provide Michael adducts. The overall transformation results in cine-substitution of the starting vinyl bromide. The Royal Society of Chemistry 2005.