3443-45-6Relevant articles and documents
Synthesis of benzo[a]pyren-6-yl-substituted carboxylic acids
Dyker, Gerald,Kadzimirsz, Daniel
, p. 3167 - 3172 (2003)
The title compounds were synthesized from benzo[a]pyrene in three to four steps, depending on the chain length of the carboxylic acid. After iodination, alkanone chains were introduced by special Heck reactions. Transformation into carboxylic acids was achieved by haloform reaction and by Willgerodt-Kindler reaction. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
Chromophore quench-Labeling: An approach to quantifying catalyst speciation as demonstrated for (EBI)ZrMe2/ b(C6F5)3?Catalyzed polymerization of 1?Hexene
Nelsen, D. Luke,Anding, Bernie J.,Sawicki, Julie L.,Christianson, Matthew D.,Arriola, Daniel J.,Landis, Clark R.
, p. 7398 - 7408 (2018/05/23)
Chromophore-containing quench agents 2 and 3 enable quantitative active site counting and determination of the mass distribution of active catalyst polymeryls by refractive index (RI) and UV detected gel permeation chromatography (GPC) for the polymerization of 1-hexene catalyzed by (EBI)ZrMe2/B(C6F5)3. Time evolution of catalyst speciation data and the time profiles of monomer consumption, end-group generation, and bulk molecular weight distribution data have been analyzed by kinetic modeling to determine rate constants for initiation by insertion of hexene into a Zr?Me bond (ki), propagation (kp), chain transfer to form vinylidene (k1,2) and vinylene (k2,1) end groups, and reinitiation from a Zr?H bond (kr). Unlike previous models that assumed fast catalyst reinitiation, this analysis reveals that kr is considerably slower than kp; catalyst speciation data are critical to making this distinction. This study demonstrates that chromophore quench-labeling with 2 and 3 enables rapid, quantitative analysis of detailed kinetic models for catalytic olefin polymerization reactions using GPC with UV and RI detectors.
Compounds for determining the activity of phospholipase A2
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, (2010/11/29)
Compounds for determining the activity of phospholipase A2, are described herein, and include embodiments having formula (1) wherein L1 is derived from an ether (R1—OR2)m, wherein R1 and R2 are independently selected and are derived from a hydrocarbon having 1 to 12 carbon atoms, with m being an integer from 1 to 4, or from a hydrocarbon R having 1 to 20 carbon atoms; F is unsubstituted or substituted pyrene as a flouraphore; Q is a quencher, and L2 is C(O)-L1 or C(O)-L1-NH, wherein L1 is as defined above. These compounds may be used to determine the activity of phospholipase A2, in particular PAF-AH.