34582-33-7

Basic information

• Product Name: H-Glu(OMe)-OtBu
• Synonyms: H-Glu(OMe)-OtBu;(S)-1-tert-butyl 5-Methyl 2-aMinopentanedioate hydrochloride;L-Glutamic acid 1-(1,1-dimethylethyl) 5-methyl ester hydrochloride;L-Glu(OMe)-OtBu·HCl;(S)-1-tert-Butyl 5-methyl 2-aminopentanedioate HCl;L-Glutamic acid γ-methyl ester α-tert-butyl ester hydrochloride≥ 98% (HPLC);L-Glu(Ome)-Otbu
• CAS NO: 34582-33-7
• Molecular Formula: C₁₀H₁₉NO₃*ClH
• Molecular Weight: 253.7231
• Mol File: 34582-33-7.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: H-Glu(OMe)-OtBu(CAS DataBase Reference)
• NIST Chemistry Reference: H-Glu(OMe)-OtBu(34582-33-7)
• EPA Substance Registry System: H-Glu(OMe)-OtBu(34582-33-7)

Safety Data

• Hazardous Substances Data: 34582-33-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

H-Glu(ome)-otbu hcl

InChI:InChI=1S/C10H19NO4.ClH/c1-10(2,3)15-9(13)7(11)5-6-8(12)14-4;/h7H,5-6,11H2,1-4H3;1H/t7-;/m0./s1

Upstream product

• 118710-00-2 DL-glutamic acid-γ-methyl ester hydrochloride 
• 115-11-7 isobutene 
• 186581-53-3 diazomethane 
• 34897-61-5 N-(benzyloxycarbonyl)-L-glutamic acid α-t-butyl ester dicyclohexylamine salt 
• 3077-51-8 γ-methyl L-glutamate hydrochloride 
• 56-86-0 L-glutamic acid 
• 617-65-2 Glutamic acid 

Downstream Products

• 130799-24-5 (S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-5-oxo-hexanoic acid tert-butyl ester 
• 118545-57-6 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-5-phenyl-(2RS)-pentanoate 
• 23736-78-9 N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester 
• 118545-54-3 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-(2S)-pentanoate 
• 125089-94-3 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-(2S)-hexanoate 
• 118545-51-0 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-(2S)-heptanoate 
• 118545-53-2 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-5-methyl-(2S)-hexanoate 
• 118545-55-4 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-6-methyl-(2S)-heptanoate 
• 125089-93-2 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-(2S)-octanoate 
• 118545-52-1 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-5-phenyl-(2S)-pentanoate 
• 125089-95-4 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-5-(4-methoxyphenyl)-(2S)-hexanoate 
• 118545-56-5 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-5-(4-nitrophenyl)-(2S)-pentanoate 
• 79648-88-7 α-tert-butyl γ-methyl N'-<4--N-methylamino>benzoyl>-L-glutamate 
• 92412-88-9 N⁵-Acetyl-N²,N²-diallyl-N⁵-benzyloxy-L-ornithin-tert-butylester 

Relevant articles and documents

SYNTHESIS OF NONPROTEINOGENIC AMINO ACIDS PART 2: PREPARATION OF A SYNTHETIC EQUIVALENT OF THE γ-ANION SYNTHON FOR ASYMMETRIC AMINO ACID SYNTHESIS

The synthesis of α-t-butyl γ-methyl N-trityl-(S)-glutamate (12) from (S)-glutamic acid (6) is described.Diester (12), on treatment with lithium isopropylcyclohexylamide followed by the addition of carbonyl compounds, reacts to give the γ-substituted glutamic acid derivatives (13a-i) with retention of optical purity at the α centre.