34604-52-9

Basic information

• Product Name: Diethylene Glycol Dimethanesulfonate
• Synonyms: Diethylene Glycol Dimethanesulfonate;2,2'-Oxybis-ethanol 1,1'-DiMethanesulfonate;2,2'-Oxybis-ethanol DiMethanesulfonate;Bis(2-Mesyloxyethyl) Ether;Diethylene Glycol DiMesylate;ENT 61168
• CAS NO: 34604-52-9
• Molecular Formula: C₆H₁₄O₇S₂
• Molecular Weight: 262.30116
• Product Categories: Aliphatics;Intermediates;Sulfur & Selenium Compounds
• Mol File: 34604-52-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 57-58 °C
• Boiling Point: 480.2 °C at 760 mmHg
• Flash Point: 244.2 °C
• Appearance: White Solid
• Density: 1.389 g/cm³
• Vapor Pressure: 6.46E-09mmHg at 25°C
• Refractive Index: 1.47
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Diethylene Glycol Dimethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Diethylene Glycol Dimethanesulfonate(34604-52-9)
• EPA Substance Registry System: Diethylene Glycol Dimethanesulfonate(34604-52-9)

Safety Data

• Hazardous Substances Data: 34604-52-9(Hazardous Substances Data)

Usage

Description

Ms-PEG3-Ms are PEG linkers with two mesyl groups. The mesyl groups are good leaving groups and can also be used as protecting groups for primary alcohols. They can be deprotected in the presence of sodium amalgam. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Chemical Properties

White Solid

Uses

Intermediate in the production of alkylating agents

InChI:InChI=1/C6H14O7S2/c1-14(7,8)12-5-3-11-4-6-13-15(2,9)10/h3-6H2,1-2H3

Upstream product

• 75-75-2 methanesulfonic acid 
• 14098-44-3 2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin 

Downstream Products

• 86955-49-9 2,2'-((oxybis(ethane-2,1-diyl))bis(oxy))bis((benzyloxy)benzene) 
• 86955-50-2 3,3'-diphenol dibenzyl ether 
• 134750-74-6 (+)-2,2'-Oxydiethylenedioxybis(2-phenylcyclophenylethyl methyl ether) 
• 134750-74-6 C₃₂H₄₆O₇ 
• 138572-09-5 4,10-Bis(p-toluenesulfonamido)-5'-nitro-2,3-dibenzo-12-crown-4 
• 86955-65-9 N-((S)-2-Hydroxy-3-{4-[2-(2-{4-[(S)-2-hydroxy-3-(isopropyl-methanesulfonyl-amino)-propoxy]-phenoxy}-ethoxy)-ethoxy]-phenoxy}-propyl)-N-isopropyl-methanesulfonamide 
• 86901-76-0 (S)-1-[4-(2-{2-[4-((S)-2-Hydroxy-3-isopropylamino-propoxy)-phenoxy]-ethoxy}-ethoxy)-phenoxy]-3-isopropylamino-propan-2-ol 
• 154875-18-0 17-Methoxy-4,10-bis-(toluene-4-sulfonyl)-7-oxa-4,10-diaza-bicyclo[11.3.1]heptadeca-1⁽¹⁶⁾,13⁽¹⁷⁾,14-triene 
• 134750-74-6 1,5-bis(2'-methoxymethoxy-1'-phenylcyclohexyloxy)-3-oxapentane 
• 86902-13-8 2-(2-phenoxyethoxy)ethyl methanesulfonate 
• 166271-30-3 (-)-1,5-bis-<2'-(benzyloxy)cyclohexyloxy>-3-oxapentane 
• 166376-78-9 (+)-1,5-bis-<2'-(benzyloxy)cyclohexyloxy>-3-oxapentane 
• 155935-06-1 C₃₈H₄₈O₇ 
• 169872-71-3 C₃₈H₄₈O₇ 

Relevant articles and documents

MODIFIED CROWN ETHER CATALYSTS. 4. CLEAVAGE OF MACROCYCLIC ETHERS BY EATON'S REAGENT (METHANESULFONIC ACID/PHOSPHORUS PENTOXIDE

Eaton's reagent (methanesulfonic acid/phosphorous pentoxide) is a superior media for the acylation of benzo crown ether compounds.Benzo-15-crown-5 was cleaved in Eaton's reagent to form methanesulfonate esters of the glycol cleavage products.A comparison of the NMR spectrum of the cleavage products with those of some of the possible products showed that the aliphatic glycols formed the major portion of the cleavage products.