347186-01-0

Basic information

• Product Name: 1-N-BOC-1,3-CYCLOHEXYLDIAMINE
• Synonyms: trans-tert-butyl 3-aminocyclohexylcarbamate(racemic);tert-Butyl 3-aMinocyclohexylcarbaMate;(3-Aminocyclohexyl)carbamic acid tert-butyl ester;tert-Butyl N-(3-aminocyclohexyl)carbamate;-N-BOC-1,3-CYCLOHEXYLDIAMINE;1-N-Boc-1,3-diaMino-cyclohexane;CarbaMicacid, N-(3-aMinocyclohexyl)-, 1,1-diMethylethyl ester;1-N-BOC-1,3-CYCLOHEXYLDIAMINE
• CAS NO: 347186-01-0
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.3
• Product Categories: N-BOC
• Mol File: 347186-01-0.mol

Chemical Properties

• Boiling Point: 322℃
• Flash Point: 149℃
• Appearance: /
• Density: 1.02
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 12.40±0.40(Predicted)
• CAS DataBase Reference: 1-N-BOC-1,3-CYCLOHEXYLDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-BOC-1,3-CYCLOHEXYLDIAMINE(347186-01-0)
• EPA Substance Registry System: 1-N-BOC-1,3-CYCLOHEXYLDIAMINE(347186-01-0)

Safety Data

• Hazardous Substances Data: 347186-01-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-N-BOC-1,3-cyclohexyldiamine is used as a building block for the synthesis of various pharmaceuticals due to its ability to contribute to the development of new drug molecules with specific therapeutic properties.
Used in Drug Formulation:
1-N-BOC-1,3-cyclohexyldiamine is used as a regulator for the controlled release of active pharmaceutical ingredients, enhancing the efficacy and safety of drug formulations.
Used in Asymmetric Synthesis:
1-N-BOC-1,3-cyclohexyldiamine is used as a chiral auxiliary in asymmetric synthesis to create enantiomerically pure compounds, which are essential for the development of drugs with improved selectivity and reduced side effects.
Used in Polymer and Material Science:
1-N-BOC-1,3-cyclohexyldiamine is used in the production of polymers and materials, contributing to the development of new materials with specific properties for various applications.

Upstream product

• 34619-03-9 tert-butyldicarbonate 
• 3385-21-5 1,3-diaminocyclohexane 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 863510-61-6 N-(tert-butoxycarbonyl)-N'-[(5-isoquinolyl)sulfonyl]-1,3-cyclohexanediamine 
• 390765-51-2 tert-butyl 3-(2,4-dioxo-3,4, 5,6,7,8-hexahydro-1(2H)-quinazolinyl)cyclohexylcarbamate 

Relevant articles and documents

FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to a class of fused pyrimidine compounds of Formula I, their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these fused pyrimidine compounds, and to pharmaceutical compositions containing them.

5-Substituted isoquinoline derivatives

A compound represented by the following formula (1) or a salt thereof: wherein R1 represents hydrogen atom, a halogen atom and the like; R2 represents hydrogen atom, a halogen atom, a C1-6 alkyl group and the like; and R3 represents —O—X—C(A1)(A11)—C(A2)(A2l)—N(A3l)(A3)(X represents propylene group etc., A11 and A21 represent hydrogen atom, or a C1-6 alkyl group, A31 represents a C1-6 alkyl group substituted with hydroxyl group, or hydrogen atom, and A1, A2, and A3 represent hydrogen atom, a C1-6 alkyl group and the like) and the like, which has an inhibitory activity on the phosphorylation of myosin regulatory light chain, and is useful for treatment of diseases relating to contraction of various cells and the like.