35213-85-5Relevant articles and documents
Efficient uncatalyzed conversion of primary and secondary thioamides into 1-substituted, 5-substituted, 1, 5-disubstituted and annulated tetrazoles
El-Ahl, Abdel-Aziz S.,Amer, Fatty A.,Elbeheery, Akram H.
experimental part, p. 2226 - 2235 (2012/03/26)
Unprecedented high-yield simple and mild conversion of primary aliphatic and aromatic thioamides into 5-substituted tetrazoles on treatment with a combination of tetrachlorosilane and sodium azide in refluxing acetonitrile has been achieved. Secondary acyclic, cyclic, and heterocyclic thioamides could also be transformed in high yields into 1-substituted, 1,5-disubstituted, or annulated tetrazoles under the same reaction condition. Copyright Taylor & Francis Group, LLC.
Microwave assisted synthesis and antifungal activity of 1,2,4-triazine, 1,2,4-triazole, tetrazole and pyrazole derivatives
Kidwai, Mazaahir,Goel, Yogesh,Kumar, Rajesh
, p. 174 - 179 (2007/10/03)
The condensation reactions of 2-hydrazino-4-methylquinoline with diethyl oxalate, ethyl bromoacetate, aromatic aldehydes, acetic anhydride, nitrous acid and different acetophenones followed by DMF and POCl3 under microwave irradiation and by conventional methods are described. The reaction rate is enhanced tremendously under microwave irradiation as compared to conventional method with improved yields. All the newly synthesised compounds have been screened for antifungal activity against fungi A. niger andA.flavous.