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Benzyl L-tryptophanate hydrochloride is a synthetic compound derived from the combination of L-tryptophan, an essential amino acid, and benzyl ester. It is a white crystalline solid that is soluble in water and exhibits hydrochloride salt properties. Benzyl L-tryptophanate hydrochloride is known for its potential applications in various fields, particularly in chemical biology and drug discovery.

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  • 35858-81-2 Structure
  • Basic information

    1. Product Name: Benzyl L-tryptophanate hydrochloride
    2. Synonyms: TRYPTOPHAN-OBZL HCL;L-TRYPTOPHAN BENZYL ESTER HYDROCHLORIDE;H-TRP-OBZL HCL;L-tryptophan benzyl ester hcl;benzyl L-tryptophanate monohydrochloride;Trp-OBzl·HCl;TRYPTOPHANBENZYLESTERMONOHYDROCHLORIDE;Benzyl L-tryptophanate hydrochloride
    3. CAS NO:35858-81-2
    4. Molecular Formula: C18H18N2O2*ClH
    5. Molecular Weight: 330.81
    6. EINECS: 252-765-7
    7. Product Categories: Amino hydrochloride
    8. Mol File: 35858-81-2.mol
  • Chemical Properties

    1. Melting Point: 222 °C(Solv: water (7732-18-5))
    2. Boiling Point: 489.9 °C at 760 mmHg
    3. Flash Point: 250.1 °C
    4. Appearance: White/Powder
    5. Density: 1.247g/cm3
    6. Vapor Pressure: 9.59E-10mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: 2-8°C
    9. Solubility: Soluble in methanol (50 mg/mL in MeOH).
    10. CAS DataBase Reference: Benzyl L-tryptophanate hydrochloride(CAS DataBase Reference)
    11. NIST Chemistry Reference: Benzyl L-tryptophanate hydrochloride(35858-81-2)
    12. EPA Substance Registry System: Benzyl L-tryptophanate hydrochloride(35858-81-2)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 35858-81-2(Hazardous Substances Data)

35858-81-2 Usage

Uses

Used in Chemical Biology:
Benzyl L-tryptophanate hydrochloride is used as a building block in chemical biology for the synthesis of various biologically active molecules. Its unique structure allows it to be incorporated into peptides and other macromolecules, enabling researchers to study protein-protein interactions and develop novel therapeutic agents.
Used in Drug Discovery:
In the field of drug discovery, Benzyl L-tryptophanate hydrochloride is utilized as a key intermediate in the development of small molecule inhibitors. These inhibitors are designed to target specific protein-protein interactions, which play a crucial role in various diseases and disorders.
Used in Preparation of Small Molecule Inhibitors:
Benzyl L-tryptophanate hydrochloride is used as a precursor in the preparation of small molecule inhibitors that target protein-protein interactions in the RAD51 family of recombinases. The RAD51 family of proteins is involved in the repair of DNA damage, and their dysregulation has been implicated in various cancers. By inhibiting these protein-protein interactions, researchers aim to develop new therapeutic strategies for the treatment of cancer and other diseases associated with DNA repair mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 35858-81-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,8,5 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35858-81:
(7*3)+(6*5)+(5*8)+(4*5)+(3*8)+(2*8)+(1*1)=152
152 % 10 = 2
So 35858-81-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H18N2O2.ClH/c19-16(18(21)22-12-13-6-2-1-3-7-13)10-14-11-20-17-9-5-4-8-15(14)17;/h1-9,11,16,20H,10,12,19H2;1H

35858-81-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
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  • Alfa Aesar

  • (H63385)  L-Tryptophan benzyl ester hydrochloride, 98%   

  • 35858-81-2

  • 1g

  • 218.0CNY

  • Detail
  • Alfa Aesar

  • (H63385)  L-Tryptophan benzyl ester hydrochloride, 98%   

  • 35858-81-2

  • 5g

  • 873.0CNY

  • Detail

35858-81-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Benzyl L-tryptophanate hydrochloride

1.2 Other means of identification

Product number -
Other names TRP-OBZLCL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35858-81-2 SDS

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