35968-89-9

Basic information

• Product Name: 2,6-Naphthyridine,3-methyl-(9CI)
• Synonyms: 2,6-Naphthyridine,3-methyl-(9CI)
• CAS NO: 35968-89-9
• Molecular Formula: C₉H₈N₂
• Molecular Weight: 144.17322
• Product Categories: ISOQUINOLINE
• Mol File: 35968-89-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-Naphthyridine,3-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Naphthyridine,3-methyl-(9CI)(35968-89-9)
• EPA Substance Registry System: 2,6-Naphthyridine,3-methyl-(9CI)(35968-89-9)

Safety Data

• Hazardous Substances Data: 35968-89-9(Hazardous Substances Data)

Usage

General Description

2,6-Naphthyridine, 3-methyl-(9CI) is a chemical compound with the molecular formula C8H7N. It is a derivative of naphthyridine, a class of organic compounds that typically contain a seven-membered ring fused to a pyridine ring. The 3-methyl substitution on the naphthyridine ring adds a methyl group to the third carbon atom, altering its chemical properties. 2,6-Naphthyridine,3-methyl-(9CI) may be used in organic synthesis or as a building block for more complex molecules. It has not been widely studied for its specific applications or biological effects, and further research may be necessary to understand its potential uses.

Upstream product

• 56752-28-4 N-(3-pyridylmethylidene)tert-butylamine 
• 80863-24-7 N-(4-pyridylmethylidene)tert-butylamine 

Relevant articles and documents

Flash vacuum thermolysis of N-(3-and 4-Pyridylmethylidene)-tert- butylamines: Mechanisms of formation of pyrrolopyridines and naphthyridines

Pyrrolopyridines and naphthyridines are formed by flash vacuum thermolysis (FVT) of 3-and 4-pyridylmethylidene-tert-butylimines 8 and 15. Elimination of a methyl radical generates resonance stablized 2-azaallyl radicals a1 and b1. The formation of pyrrolopyridines 9, 16 and 17 is rationalized in terms of cyclization of 1-aziridinyl radicals a2 and b2. Formation of naphthyridine 10 from imine 8, and of 11 and 18 from imine 15, are in accord with cyclization of 1-azaallyl radicals a6 and b9. Formation of naphthyridine 11 from 8, and of 10 and 19 from 15, indicate the operation of the spiro-cyclization pathways forming intermediates a9 and b14. Formation of the 1,8-naphthyridine 20 (3%) indicates a rearrangement through aziridine b22 and biradical b23. DFT calculations at the CAM-B3LYP/6-311G(d,p) level support the proposed reaction mechanisms.