36234-16-9Relevant articles and documents
Tetrahydro-4 H-pyran-4-one: From the Laboratory Scale to Pilot Plant Manufacture
Zahim, Sara,Delacroix, Kenny,Carlier, Agathe,Berranger, Thierry,Bergraser, Julie,Echeverria, Pierre-Georges,Petit, Laurent
, p. 199 - 206 (2022/01/12)
This study describes our recent efforts to find an efficient and scalable route to tetrahydro-4H-pyran-4-one using the commercially available starting materials. The route scouting work and the full development of an efficient access to the target are described. This work culminated in the preparation of above 20 kg of the title compound in our pilot plant facility.