36913-39-0 Usage
Uses
Different sources of media describe the Uses of 36913-39-0 differently. You can refer to the following data:
1. Dopaminergic neurotoxin; a selective cytostatic agent in small-cell lung cancer cell lines with neuroendocrine properties.
2. MPP+ iodide is an active metabolite of the dopaminergic neurotoxin MPTP.
General Description
1-Methyl-4-phenylpyridinium (MPP+) induces neurotoxicity by inhibiting mitochondrial redox functions in the striatal synaptosomes. It is a potential neurotoxin and induces Parkinson′s disease in animal models. It mediates apoptosis by the generation of reactive oxygen species in cerebellar granule neurons and neuroblastoma cells. MPP+ modulates the distribution of dopamine. It elicits neurotoxicity by activating neuronal nitric oxide synthase (nNOS), resulting in excess nitric oxide.
Biochem/physiol Actions
MPP+ iodide is an active metabolite of dopaminergic neurotoxin MPTP.
Check Digit Verification of cas no
The CAS Registry Mumber 36913-39-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,9,1 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 36913-39:
(7*3)+(6*6)+(5*9)+(4*1)+(3*3)+(2*3)+(1*9)=130
130 % 10 = 0
So 36913-39-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H9N.HI/c1-2-4-10(5-3-1)11-6-8-12-9-7-11;/h1-9H;1H
36913-39-0Relevant articles and documents
Cation-π interactions secure aggregation induced emission of planar organic luminophores
Leduskrasts, Kaspars,Kinens, Artis,Suna, Edgars
, p. 12663 - 12666 (2019)
The use of non-covalent intermolecular π+-π interactions between quaternary pyridinium or imidazolium cations and aromatic π systems is an efficient approach to achieve AIE in planar purely organic luminophores.
MATERIALS FOR USE IN AN AQUEOUS ORGANIC REDOX FLOW BATTERY
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Paragraph 0256; 0260, (2018/05/15)
Described herein are aqueous organic redox flow batteries that include a first redox active material that can include a metallocene or a salt thereof, and a second redox active material that can include a viologen or a salt thereof. The aqueous organic re
Photophysical and electrochemical properties of platinum(ii) complexes bearing a chromophore-acceptor dyad and their photocatalytic hydrogen evolution
Zhang, Gui-Ju,Gan, Xin,Xu, Quan-Qing,Chen, Yong,Zhao, Xi-Juan,Qin, Biao,Lv, Xiao-Jun,Lai, Siu-Wai,Fu, Wen-Fu,Che, Chi-Ming
experimental part, p. 8421 - 8429 (2012/07/30)
A series of platinum(ii) complexes bearing a chromophore-acceptor dyad obtained by reacting 4-(p-bromomethylphenyl)-6-phenyl-2,2′-bipyridine or 4′-(p-bromomethylphenyl)-2,2′:6′,2′′-terpyridine with pyridine, 4-phenylpyridine, 4,4′-bipyridine, 1-methyl-4-(