374-46-9

Basic information

• Product Name: 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL
• Synonyms: 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL
• CAS NO: 374-46-9
• Molecular Formula: C5H7F5O
• Molecular Weight: 178.1
• Mol File: 374-46-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 90-92
• Flash Point: 32.6°C
• Appearance: /
• Density: 1.24
• Vapor Pressure: 4.38mmHg at 25°C
• Refractive Index: 1.3292
• CAS DataBase Reference: 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL(374-46-9)
• EPA Substance Registry System: 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL(374-46-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 374-46-9(Hazardous Substances Data)

Usage

General Description

1,1,1,2,2-Pentafluoro-3-methylbutan-3-ol is a chemical compound with the molecular formula C5H8F5O. It is a fluorinated alcohol that is commonly used in the production of pharmaceuticals, agrochemicals, and as a solvent in various industrial processes. It is a colorless liquid with a strong, sweet odor, and it is highly flammable. 1,1,1,2,2-Pentafluoro-3-methylbutan-3-ol is also used as a reagent in organic synthesis, particularly in the preparation of fluorinated compounds. Additionally, it is considered to be a volatile organic compound (VOC) and can contribute to air pollution if released into the atmosphere. Therefore, proper handling and disposal of this chemical are important to minimize its environmental impact.

InChI:InChI=1/C5H7F5O/c1-3(2,11)4(6,7)5(8,9)10/h11H,1-2H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 426-65-3 ethyl Pentafluoropropionate 
• 142-96-1 dibutyl ether 
• 422-64-0 pentafluoropropionic acid 
• 378-75-6 perfluoropropionic acid methyl ester 
• 67-64-1 acetone 
• 56184-59-9 (pentafluoro ethyl) magnesiumbromide 

Relevant articles and documents

Estimation of hydrocarbon solubilities in hydrofluorocarbons

A new solubility parameter, SP, for hydrofluorocarbons (HFCs) has been developed (SP = 1.175 ln(np) + 0.025H - 0.063F - 0.028α - 0.018β where np depends on the molar volume and the molar refractivity; H and F are the number of hydrogens and fluorines, respectively, in the molecule; and α and β are the respective numbers of H-C-F and H-C-C-F connections).Values of SP have been used to predict if an HFC would be a good solvent for various hydrocarbons at 25 deg C.Within an isomeric HFC family, the individual HFCs having the greatest solvency for hydrocarbons were those having the maximum separation of fluorines from hydrogens.Hildebrand solubility parameters, δ, are compared with the semi-empirical SP values.Syntheses for 10 new compounds are given: 3,3,4,4,5,5,6,6,7,7-decafluorononane, 1,1,1,2-tetrafluoro-2-(trifluoromethyl)-3-methylbutane, 1,1,1,2,2-pentafluoro-3-methylbutane, 1,1,1,2,2,3,3,4,4-nonafluoro-5-methylhexane, 1,1,1,2,2,3,3,4,4-nonafluoroheptane, 1,1,1,2-tetrafluoro-2-(trifluoromethyl)butane, 1,1,1-trifluoro-3-(trifluoromethyl)butane, 1,1,1,2,2,3,3,5-octafluorohexane, 1,1,1,2,2-pentahydroperfluorooctane and 1,1,1,2,2-pentahydroperfluorodecane.