37455-53-1Relevant articles and documents
TRIAZINE COMPOUNDS AS KINASE INHIBITORS
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Page/Page column 101, (2009/09/05)
The present invention relates to triazine compounds that are useful as kinase inhibitors. More particularly, the present invention relates to morpholino substituted triazines, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative disorders including tumours and cancers as well as other disorders or conditions related to or associated with mTOR kinases or PI3 kinases. The compounds are of the formula (I)
Synthesis of Some Alkyl- and Arylimidazoles
Watanabe, T.,Nishiyama, J.,Hirate, R.,Uehara, K.,Inoue, M.,et al.
, p. 1277 - 1281 (2007/10/02)
The pyrolysis of 2-azidopyrazines led to give 1-cyanoimidazoles, which were hydrolyzed in alkaline and acidic media to the corresponding imidazoles.This ring transformation occured also by photolysis.