376637-08-0

Basic information

• Product Name: 1,2-bis(4-bromophenyl)-1H-pyrrole
• Synonyms: 1,2-bis(4-bromophenyl)-1H-pyrrole
• CAS NO: 376637-08-0
• Molecular Weight: 377.078
• Mol File: 376637-08-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-bis(4-bromophenyl)-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(4-bromophenyl)-1H-pyrrole(376637-08-0)
• EPA Substance Registry System: 1,2-bis(4-bromophenyl)-1H-pyrrole(376637-08-0)

Safety Data

• Hazardous Substances Data: 376637-08-0(Hazardous Substances Data)

Upstream product

• 842123-96-0 1-(4-bromophenyl)-3-(1,3-dioxolan-2-yl)-1-propanone 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 376634-54-7 tert-butyl (E)-3-[4-(1-{4-[(E)-3-(tert-butoxy)-3-oxo-1-propenyl]phenyl}-1H-pyrrol-2-yl)phenyl]-2-propenoate 

Relevant articles and documents

Tyrosine phosphatase inhibitors

A compound of the formula (I): wherein X1 and X2 are the same or different and each is a bond or a spacer having 1 to 20 atom(s) in the main chain; one of R1 and R2 is a cycle group having substituent(s) selected from 1) an optionally substituted carboxy-C1-6 alkoxy group and 2) an optionally substituted carboxy-C1-6 aliphatic hydrocarbon group, wherein the cycle group optionally has additional substituent(s), and the other is an optionally substituted cycle group or a hydrogen atom; and R3, R4 and R5 are the same or different and each is a hydrogen atom or a substituent, or R4 may link together with R3 or R5 to form an optionally substituted ring; provided that when R3 is a hydrogen atom, R4 is a hydrogen atom and R5 is methyl, X2—R2 is not 4-cyclohexylphenyl; when R3 is 4-methoxyphenyl, R4 is a hydrogen atom and R5 is methyl, X2—R2 is not 4-methoxyphenyl; and when R1 or R2 is a hydrogen atom, the adjacent X1 or X2 is not a C1-7 alkylene; or a salt thereof exhibits a protein tyrosine phosphatase inhibitory action and is useful as a prophylactic or therapeutic agent for diabetes or the like.