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Cas Database

37795-40-7

37795-40-7

Identification

  • Product Name:5β‐estrane‐3β,17β‐diol

  • CAS Number: 37795-40-7

  • EINECS:

  • Molecular Weight:278.435

  • Molecular Formula: C18H30O2

  • HS Code:

  • Mol File:37795-40-7.mol

Synonyms:

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Relevant articles and documentsAll total 1 Articles be found

PROGESTERONE RECEPTOR ANTAGONISTS AND USES THEREOF

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Page/Page column 68-69, (2011/11/30)

The present invention relates to a compound of formula (I): for its use as progesterone receptor antagonist, in particular for its use for the prevention and/or the treatment of cancer or uterine pathologies.

Process route upstream and downstream products

Process route

Estrone
53-16-7

Estrone

5β‐estrane‐3α,17β‐diol
10002-97-8

5β‐estrane‐3α,17β‐diol

5β‐estrane‐3β,17β‐diol
37795-40-7

5β‐estrane‐3β,17β‐diol

Conditions
Conditions Yield
With hydrogenchloride; platinum; Hydrogenation;
Conditions
Conditions Yield
Oestr-5(10)-en-3β,17β-diol 6b, Ru-oxid, Hydrierung;
5(10)-Estren-3-on-17β-ol, RuO2/H2;
Estran, RuO2/H2;
Conditions
Conditions Yield
Oestratrien-(A)-diol, Rutheniumdioxyd, A., wenig wss. NaOH, 65grad, 100 at, Hydrieren, neben 5α,10α-Oestradiol-(3β,17β);
Oestr-5(10)-en-3α,17β-diol, H2, Ru-oxid, neben sehr wenig 5β-Estran-3α,17β-diol;
Oestr-5(10)-en-3α,17β-diol, H2, Rhodium-Aluminium, neben sehr wenig 5β-Estran-3α,17β-diol;
Conditions
Conditions Yield
19-Norandrosten-17β-ol-3-on, NaBH4;
19-Nor-androstandion-(3,17), NaBH4, wss. Propanol-(2), Me., neben 3β-Hydroxy-19-nor-androstanon-(17);
Conditions
Conditions Yield
5β-Oestrandiol-(3α,17β)-acetat-(17β), Me., wenig W., KOH, Kochen;
5β-Oestranol-(3α)-on-(17), NaBH4, Stehenlassen;
Conditions
Conditions Yield
Oestratrien-(A)-diol, Rutheniumdioxyd, A., wenig wss. NaOH, 65grad, 100 at, Hydrieren, neben 5α,10α-Oestradiol-(3α,17β);

37795-40-7 Upstream products

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