380227-23-6

Basic information

• Product Name: cis-(+)-6-(3,4-diethoxybenzoyl)cyclohex-3-enecarboxylic acid
• CAS NO: 380227-23-6
• Molecular Weight: 318.37
• Mol File: 380227-23-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: cis-(+)-6-(3,4-diethoxybenzoyl)cyclohex-3-enecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cis-(+)-6-(3,4-diethoxybenzoyl)cyclohex-3-enecarboxylic acid(380227-23-6)
• EPA Substance Registry System: cis-(+)-6-(3,4-diethoxybenzoyl)cyclohex-3-enecarboxylic acid(380227-23-6)

Safety Data

• Hazardous Substances Data: 380227-23-6(Hazardous Substances Data)

Upstream product

• 2050-46-6 1,2-diethoxybenzene 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 

Downstream Products

• 415927-53-6 4-[(4aS,8aR)-4-(3,4-Diethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl]-benzoic acid 

Relevant articles and documents

Novel selective phosphodiesterase (PDE4) inhibitors. 4. Resolution, absolute configuration, and PDE4 inhibitory activity of cis-tetra- and cis-hexahydrophthalazinones

Recently, we reported that 4-catechol-substituted cis-(±)-4a,5,6,7,8,8a-hexa- and cis-(±)- 4a,5,8,8a-tetrahydro-2H-phthalazin-1-ones show potent inhibition of phosphodiesterase (PDE4) activity, while the corresponding trans racemic mixtures exhibit only w