383868-64-2

Basic information

• Product Name: 1-benzyloxy-4-broMo-2-nitrobenzene
• Synonyms: 1-benzyloxy-4-broMo-2-nitrobenzene
• CAS NO: 383868-64-2
• Molecular Formula: C₁₃H₁₀BrNO₃
• Molecular Weight: 308
• Mol File: 383868-64-2.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-benzyloxy-4-broMo-2-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyloxy-4-broMo-2-nitrobenzene(383868-64-2)
• EPA Substance Registry System: 1-benzyloxy-4-broMo-2-nitrobenzene(383868-64-2)

Safety Data

• Hazardous Substances Data: 383868-64-2(Hazardous Substances Data)

Usage

General Description

1-benzyloxy-4-bromo-2-nitrobenzene is an organic compound with the chemical formula C13H10BrNO3. It is a nitrobenzene derivative, containing a benzene ring with a bromine and a nitro group attached to it. Additionally, there is a benzyloxy group linked to the benzene ring, which consists of a benzene group connected to an oxygen atom. 1-benzyloxy-4-broMo-2-nitrobenzene is commonly used in organic synthesis and pharmaceutical research due to its versatile reactivity and potential pharmacological properties.

Upstream product

• 7693-52-9 4-bromo-2-nitrophenol 
• 100-44-7 benzyl chloride 
• 106-41-2 4-bromo-phenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 865716-20-7 2-({3-[4-(benzyloxy)-3-nitrophenyl]prop-2-ynyl}oxy)tetrahydro-2H-pyran 
• 515152-69-9 2-benzyloxy-5-vinylnitrobenzene 
• 1218817-33-4 1-(benzyloxy)-2-nitro-4-(oct-1-ynyl)benzene 
• 941311-41-7 2-benzyloxy-6-{4-[4-benzyloxy-3-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-butoxy}-N,N-dimethylbenzamide 
• 941311-22-4 N-[4'-benzyloxy-3'-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-biphenyl-3-yl]-2,2,2-trifluoroacetamide 
• 941311-23-5 1-[4'-benzyloxy-3'-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-biphenyl-3-yl]-3-ethyl-urea 
• 941311-12-2 2-[4-benzyloxy-3-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-pyrrole-1-carboxylic acid tert-butyl ester 
• 941311-33-7 5-[2-benzyloxy-5-(4-fluorophenylethynyl)-phenyl]-1,1-dioxo-1,2,5-thiadiazolidin-3-one 
• 941311-16-6 methanesulfonic acid 4'-benzyloxy-3'-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-biphenyl-3-yl ester 
• 941311-09-7 2-benzyloxy-5-bromophenyl-N-(t-butoxycarbonylsulfamoyl)-acetic acid ethyl ester 
• 941311-42-8 5-[2-benzyloxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-1,1-dioxo-1,2,5-thiadiazolidin-3-one 

Relevant articles and documents

WDR5-MYC INHIBITORS

Substituted N-phenyl sulfonamide compounds inhibit WDR5-MYC interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction

The treatment of tumors driven by overexpression or amplification of MYC oncogenes remains a significant challenge in drug discovery. Here, we present a new strategy toward the inhibition of MYC via the disruption of the protein-protein interaction betwee

A practical nickel-catalyzed reductive alkylation of amidophenyl bromides

A modified Weix's reductive coupling for alkylation of amidoaryl bromides based on Ni(COD)2 precatalyst and 2,2′-dipyridyl ligand was developed. This reaction is reliable for amidophenyl bromides and gives yields up to 87%, and is potentially useful in the synthesis of amidophenyl-containing molecules.