386224-25-5

Basic information

• Product Name: 2-Cyclopenten-1-ol, 1-methyl-2-pentyl-
• CAS NO: 386224-25-5
• Molecular Formula: C11H20O
• Molecular Weight: 168.279
• Mol File: 386224-25-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Cyclopenten-1-ol, 1-methyl-2-pentyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-ol, 1-methyl-2-pentyl-(386224-25-5)
• EPA Substance Registry System: 2-Cyclopenten-1-ol, 1-methyl-2-pentyl-(386224-25-5)

Safety Data

• Hazardous Substances Data: 386224-25-5(Hazardous Substances Data)

Upstream product

• 4819-67-4 2-pentyl-cyclopentanone 
• 42558-01-0 2-(1-hydroxypentyl)-cyclopentanone 
• 110-62-3 pentanal 
• 120-92-3 cyclopentanone 
• 25564-22-1 2-pentyl-2-cyclopenten-1-one 
• 917-54-4 methyllithium 
• 628-71-7 1-Heptyne 

Downstream Products

• 1128-08-1 dihydro-cis-jasmone 

Relevant articles and documents

A three-component coupling approach to cyclopentanoids

A new approach to 2,3-disubstituted cyclopentenones has been developed. This approach consists of a two-step protocol involving the cyclization of a Z-vinyl bromide under Barbier type conditions to form a cyclopentenol, which is then oxidatively rearranged to generate the cyclopentenone. The Z-vinyl bromide is in turn derived from a ruthenium catalyzed three-component coupling of an alkyne, an enone, and a HBr equivalent. A range of 2,3-disubstituted cyclopentenones has been generated, including short syntheses of jasmone and dihydrojasmone. Further applicability of this strategy is shown in the total syntheses of tetrahydrodicranenone B, rosaprostol, and a selective COX-2 inhibitor.