38707-70-9

Basic information

• Product Name: 8-Quinolinecarbaldehyde
• Synonyms: TIMTEC-BB SBB010129;RARECHEM AM LA 0004;RARECHEM AK ML 0564;QUINOLINE-8-CARBALDEHYDE;QUINOLINE-8-CARBOXALDEHYDE;8-QUINOLINECARBALDEHYDE;8-QUINOLINECARBOXALDEHYDE;AKOS BBS-00005342
• CAS NO: 38707-70-9
• Molecular Formula: C₁₀H₇NO
• Molecular Weight: 157.17
• Product Categories: ALDEHYDE;Aldehydes;Quinolines, Isoquinolines & Quinoxalines;Quinoline Derivertives;quinoline;Quinolines, Isoquinolines & Quinoxalines
• Mol File: 38707-70-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 95-96°C
• Boiling Point: 314.3°C at 760 mmHg
• Flash Point: 151.9°C
• Appearance: /
• Density: 1.223g/cm³
• Vapor Pressure: 0.00047mmHg at 25°C
• Refractive Index: 1.687
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 3.45±0.17(Predicted)
• Water Solubility: Insoluble in water.
• Sensitive: Air Sensitive
• BRN: 113039
• CAS DataBase Reference: 8-Quinolinecarbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Quinolinecarbaldehyde(38707-70-9)
• EPA Substance Registry System: 8-Quinolinecarbaldehyde(38707-70-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36/38-43
• Safety Statements: 26-37/39-36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 38707-70-9(Hazardous Substances Data)

Usage

Chemical Properties

Off-white solid

Uses

Quinoline-8-carboxaldehyde is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

InChI:InChI=1/C10H7NO/c12-7-9-4-1-3-8-5-2-6-11-10(8)9/h1-7H

Upstream product

• 622-72-0 N-(4-methoxylbenzylidene)benzylamine 
• 7496-46-0 8-bromomethyl-quinoline 

Downstream Products

• 130161-07-8 8-[N-(p-ethoxyphenyl)formimidoyl]quinoline 
• 78759-47-4 8-quinolinecarboxaldehyde tosylhydrazone 
• 340728-47-4 8-[N-(4-chlorophenyl)iminomethyl]quinoline 
• 898224-71-0 (S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-3-{[1-quinolin-8-yl-meth-(E)-ylidene]-amino}-phenyl)-propionic acid methyl ester 
• 340728-57-6 4-N-(4-methylphenyl)amino-4-(8-quinolinyl)-1-butene 
• 340728-56-5 N-(p-methoxyphenyl)-N-[1-(8-quinolyl)but-3-enyl]amine 
• 340728-60-1 4-[N-allyl,N-(4-methylphenyl)]amino-4-(8-quinolinyl)-1-butene 
• 367523-45-3 (4-ethoxy-phenyl)-(1-quinolin-8-yl-but-3-enyl)-amine 
• 74028-27-6 4-[(Quinolin-8-ylmethyl)-amino]-benzenesulfonamide 
• 54-01-3 4-(trans-2-[8]quinolyl-vinyl)-aniline 
• 917965-83-4 tert-butyl [quinolin-8-yl(toluene-4-sulfonyl)methyl]carbamate 
• 106335-97-1 trans-{PtCl₂(quinoline-8-carboxaldehyde)AsTol₃} 

Relevant articles and documents

Metal Ion-Driven Constitutional Adaptation in Dynamic Covalent C=C/C=N Organo-Metathesis

Knoevenagel barbiturate derivatives and imines are able to undergo efficient component recombination through dynamic covalent C=C/C=N organo-metathesis in absence of a catalyst. A [2×2] dynamic covalent library (DCL) containing two Knoevenagel derivatives Kn1 and Kn2 and two imines A1 and A2 has been established and its adaptive features in response to the addition of metal cations have been investigated. Addition of Cu(I) triflate as an effector, induces fast and remarkable constitutional selection of the DCL towards amplification of the Cu(I)-A2 complex and its agonist Kn1. This adaptation process could be reversed by addition of neocuproine as a competitive Cu(I) ligand. Furthermore, separate addition of five other metal cations as input agents, i. e. Ag(I), Fe(II), Zn(II), Cu(II) and Li(I), led to the generation of cation-specific distribution patterns as outputs, showing the ability of the present DCL to recognize different effectors.