3871-20-3Relevant articles and documents
PHOSPHATE AND PHOSPHONATE BASED COMPOUNDS OF 6-THIO-2'-DEOXYGUANOSINE AS ANTI-CANCER AGENTS
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Paragraph 00226, (2020/08/22)
Phosphates and phosphonates compounds of 6-thio-2'-deoxyguanosine are provided. The uses and pharmaceutical compositions of these compounds are disclosed.
Novel flame-retarding and crosslinkable multifunctional compound for prepation of polyurethane, polyurea or hybrid polymer thereof
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Paragraph 0103; 0105, (2019/08/14)
The present invention refers to novel flame retardant and crosslinkable a colored compound, for manufacturing method, and by using them flame-retardant high pressure liquid coolant and a thermosetting polyurethane or polyurea to number are disclosed. (by machine translation)
Activating water: Important effects of non-leaving groups on the hydrolysis of phosphate triesters
Kirby, Anthony J.,Medeiros, Michelle,Oliveira, Pedro S. M.,Orth, Elisa S.,Brandao, Tiago A. S.,Wanderlind, Eduardo H.,Amer, Almahdi,Williams, Nicholas H.,Nome, Faruk
supporting information; experimental part, p. 14996 - 15004 (2012/02/03)
The high rate of spontaneous hydrolysis of tris-2-pyridyl phosphate (TPP) is explained by the activating effects of the non-leaving ("spectator" ) groups on P-OAr cleavage, and not by intramolecular catalysis. Previous work on phosphate-transfer reactions has concentrated on the contributions to reactivity of the nucleophile and the leaving group, but our results make clear that the effects of the non-leaving groups on phosphorus can be equally significant. Rate measurements for three series of phosphate triesters showed that sensitivities to the non-leaving groups are substantial for spontaneous hydrolysis reactions, although significantly smaller for reactions with good nucleophiles. There are clear differences between triaryl and dialkyl aryl triesters in sensitivities to leaving and non-leaving groups with the more reactive triaryl systems showing lower values for both βLG and βNLG. Intramolecular catalysis of the hydrolysis of TPP by the neighbouring pyridine nitrogens is insignificant, primarily because of their low basicity.