3899-93-2

Basic information

• Product Name: Phenol,4-amino-, 1-(4-methylbenzenesulfonate)
• Synonyms: Phenol,4-amino-, 4-methylbenzenesulfonate (ester) (9CI); Phenol, p-amino-, p-toluenesulfonate (ester) (7CI,8CI); 4-(4-Toluenesulfonyloxy)aniline; 4-Aminophenyl tosylate; 4-Methylbenzenesulfonic acid4-aminophenyl ester; p-Toluenesulfonic acid p-aminophenyl ester
• CAS NO: 3899-93-2
• Molecular Formula: C₁₃H₁₃NO₃S
• Molecular Weight: 263.3122
• Mol File: 3899-93-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 440.5 °C at 760 mmHg
• Flash Point: 220.2 °C
• Density: 1.305 g/cm³
• CAS DataBase Reference: Phenol,4-amino-, 1-(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol,4-amino-, 1-(4-methylbenzenesulfonate)(3899-93-2)
• EPA Substance Registry System: Phenol,4-amino-, 1-(4-methylbenzenesulfonate)(3899-93-2)

Safety Data

• Hazardous Substances Data: 3899-93-2(Hazardous Substances Data)

Usage

General Description

Phenol, 4-amino-, 1-(4-methylbenzenesulfonate) is a chemical compound with the molecular formula C13H13NO3S. It is a derivative of phenol, containing an amino group at the 4-position and a sulfonate group attached to the 1-position of a methylbenzene ring. Phenol,4-amino-, 1-(4-methylbenzenesulfonate) is commonly used in organic synthesis, as a reagent in the preparation of pharmaceuticals and other organic compounds. It has also been studied for its potential biological activities and is of interest in the field of medicinal chemistry. Overall, phenol, 4-amino-, 1-(4-methylbenzenesulfonate) is a versatile chemical with various applications in the pharmaceutical and chemical industries.

Upstream product

• 536-57-2 p-toluene sulfinic acid 
• 586-96-9 Nitrosobenzene 
• 123-30-8 4-amino-phenol 
• 98-59-9 p-toluenesulfonyl chloride 
• 6324-15-8 toluene-4-sulfonic acid 4-bromo-phenyl ester 
• 301337-51-9 toluene-4-sulfonic acid 4-acetylaminophenyl ester 
• 106-45-6 para-thiocresol 
• 100-02-7 4-nitro-phenol 
• 1153-45-3 4-nitrophenyl 4-methylbenzenesulfonate 
• 100-65-2 N-Phenylhydroxylamine 

Downstream Products

• 84573-28-4 4-{[(4-methylphenyl)sulfonyl]amino}phenyl 4-methylbenzenesulfonate 
• 86317-94-4 N-<4-(4-Methylphenylsulfonyloxy)phenyl>-N'-phenylbenzamidin 
• 196208-57-8 4-azidophenyl tosylate 
• 899438-84-7 4-amino-3-bromophenyl 4-methylbenzenesulfonate 
• 255375-70-3 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 4-methylbenzenesulfonate 
• 1311946-59-4 4-[3-(2-chloroethyl)ureido]phenyl 4-methylbenzenesulfonate 
• 1311946-43-6 4-(2-oxoimidazolidin-1-yl)phenyl 4-methylbenzenesulfonate 
• 1638490-46-6 4-propionamidophenyl 4-methylbenzenesulfonate 
• 1638490-77-3 4-(2-oxo-4-phenylquinolin-1(2H)-yl)phenyl 4-methylbenzenesulfonate 
• 1098336-64-1 toluene-4-sulfonic acid 4-trifluoromethoxy-phenyl ester 
• 1135-12-2 p-benzylaniline 
• 1351762-64-5 toluene-4-sulfonic acid 4-[bis(4-nitrobenzyl)amino]phenyl ester 
• 1351762-63-4 toluene-4-sulfonic acid 4-[bis-(4-methylbenzyl)amino]phenyl ester 
• 1351762-70-3 toluene-4-sulfonic acid 4-[bis(3-nitrobenzyl)amino]phenyl ester 

Relevant articles and documents

A mild and selective Cu(II) salts-catalyzed reduction of nitro, azo, azoxy, N-aryl hydroxylamine, nitroso, acid halide, ester, and azide compounds using hydrogen surrogacy of sodium borohydride

The first mild, in situ, single-pot, high-yielding well-screened copper (II) salt-based catalyst system utilizing the hydrogen surrogacy of sodium borohydride for selective hydrogenation of a broad range of nitro substrates into the corresponding amine under habitancy of water or methanol like green solvents have been described. Moreover, this catalytic system can also activate various functional groups for hydride reduction within prompted time, with low catalyst-loading, without any requirement of high pressure or molecular hydrogen supply. Notably, this system explores a great potential to substitute expensive traditional hydrogenation methodologies and thus offers a greener and simple hydrogenative strategy in the field of organic synthesis.

AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS

In one aspect, the present disclosure provides methods of preparing a primary or secondary amine and hydroxylated aromatic compounds. In some embodiments, the aromatic compound may be unsubstituted, substituted, or contain one or more heteroatoms within the rings of the aromatic compound. The methods described herein may be carried out without the need for transition metal catalysts or harsh reaction conditions.

Photosensitive chiral self-assembling materials: Significant effects of small lateral substituents

Novel azobenzene-based photosensitive mesogens with lactate chiral units were synthesized. In order to modify the rate of the thermal Z-E isomerization of these compounds, small lateral substituents were introduced into their core in the proximity of the azo group. The influence of lateral substitution on the kinetics of the Z-E isomerization, mesomorphic behaviour, and UV-Vis absorption spectra was studied. It was found that the position of the substituents in the azobenzene core significantly affects the rate of their thermal isomerization. The stability of Z-isomers of several studied compounds is comparable to that of compounds with complex molecular structures designed for optical data storage. Although lateral substitution influences the breadth/length ratio of the core, liquid-crystalline properties of the studied materials have been preserved.