395095-62-2

Basic information

• Product Name: C₂₀H₃₆F₂NO₁₀P
• CAS NO: 395095-62-2
• Molecular Weight: 519.477
• Mol File: 395095-62-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₃₆F₂NO₁₀P(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₃₆F₂NO₁₀P(395095-62-2)
• EPA Substance Registry System: C₂₀H₃₆F₂NO₁₀P(395095-62-2)

Safety Data

• Hazardous Substances Data: 395095-62-2(Hazardous Substances Data)

Upstream product

• 80077-72-1 diethyl difluoro(trimethylsilyl)methylphosphonate 
• 219617-09-1 methyl (2S)-2-{(tert-butoxy)-N-[(tert-butyl)oxycarbonyl]carbonylamino}-4-oxobutanoate 
• 224192-24-9 methyl (2S)-2-{(tert-butoxy)-N-[(tert-butyl)oxycarbonyl]carbonylamino}-4-hydroxybutanoate 
• 219617-08-0 dimethyl (2S)-2-{(tert-butoxy)-N-[(tert-butyl)oxycarbonyl]carbonylamino}butanedioate 

Relevant articles and documents

Difluoromethylene analogues of aspartyl phosphate: The first synthetic inhibitors of aspartate semi-aldehyde dehydrogenase

The difluoromethylene analogue of aspartyl phosphate 6 has been prepared by the fluoride catalysed coupling of diethyl trimethyisilyldifluoromethyl phosphonate with an appropriate aldehyde followed by Dess-Martin oxidation and deprotection; the deprotected compound inhibited (K1 95 μM) aspartate semi-aldehyde dehydrogenase, a key enzyme involved in bacterial amino acid and peptidoglycan biosynthesis.