39514-19-7

Basic information

• Product Name: 1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: N-BENZYL-4-CARBETHOXY-3-PIPERIDONE;N-Benzyl-3-oxo-4-piperidinecarboxylate;1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER;ETHYL N-BENZYL-3-KETOPIPERIDINE-4-CARBOXYLATE;ethyl 1-benzyl-3-oxopiperidine-4-carboxylate;3-Oxo-1-(phenylmethyl)-4-piperidinecarboxylic acid ethyl ester;3-Oxo-1-phenylmethyl-4-piperidinecarboxylic acid ethyl ester;4-piperidinecarboxylic acid, 3-oxo-1-(phenylmethyl)-, ethyl ester
• CAS NO: 39514-19-7
• Molecular Formula: C₁₅H₁₉NO₃
• Molecular Weight: 261.32
• EINECS: 254-482-4
• Mol File: 39514-19-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 368.6 °C at 760 mmHg
• Flash Point: 176.7 °C
• Appearance: /
• Density: 1.154
• Vapor Pressure: 1.26E-05mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: 2-8°C
• PKA: 10.85±0.20(Predicted)
• CAS DataBase Reference: 1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER(39514-19-7)
• EPA Substance Registry System: 1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER(39514-19-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 39514-19-7(Hazardous Substances Data)

Usage

General Description

1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER is a chemical compound with the molecular formula C18H21NO4. It is an ester derivative of piperidine-4-carboxylic acid, and it contains a benzyl group attached to the nitrogen atom. 1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various piperidine-based compounds. It may also have potential applications in the development of new medications, particularly in the field of neurological and psychiatric disorders. Additionally, it may have uses as a research tool in the study of piperidine derivatives and related compounds.

InChI:InChI=1/C15H19NO3/c1-2-19-15(18)13-8-9-16(11-14(13)17)10-12-6-4-3-5-7-12/h3-7,13H,2,8-11H2,1H3

Upstream product

• 71233-25-5 ethyl 1-tert-butoxycarbonyl-3-oxopiperidine-4-carboxylate 
• 100-52-7 benzaldehyde 
• 618-32-6 Benzoyl bromide 
• 70637-75-1 ethyl 3-oxopiperidine-4-carboxylate 
• 6436-90-4 ethyl 2-(benzylamino)acetate 
• 100-46-9 benzylamine 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 52763-21-0 ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydrochloride 
• 63876-32-4 4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester 

Downstream Products

• 214551-59-4 1-Benzyl-5-(3-fluoro-phenylamino)-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester 
• 214551-61-8 1-Benzyl-5-(3-methoxy-phenylamino)-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester 
• 214551-58-3 1-Benzyl-5-(4-chloro-phenylamino)-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester 
• 72738-08-0 1-benzyl-5-(4-methoxy-anilino)-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester 
• 214551-56-1 1-Benzyl-5-phenylamino-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester 
• 214551-60-7 1-Benzyl-5-(3-chloro-phenylamino)-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester 
• 214551-57-2 1-Benzyl-5-(4-fluoro-phenylamino)-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester 
• 217488-44-3 allyl 1-benzyl-3-oxo-4-piperidinecarboxylate 
• 351038-51-2 1-benzyl-3-piperidone-4-carboxylic acid benzyl ester 
• 70637-75-1 ethyl 3-oxopiperidine-4-carboxylate 
• 957438-14-1 7-benzyl-2-morpholin-4-yl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one 
• 62259-92-1 7-benzyl-2-methyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one 
• 1112190-18-7 C₁₇H₂₁N₃O 
• 62458-96-2 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-ol 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF PRODUCING PYRAZOLO[1,5-A] PYRIMIDINE DERIVATIVES

Processes and intermediates useful for producing pyrazolo[1,5-a] pyrimidine derivatives.

With the biological activity of 5, 6, 7, 8 - tetrahydro-pyrido [3, 4 - d] pyrimidine compound and its preparation method and application (by machine translation)

The invention discloses a has biological activity of 5, 6, 7, 8 - tetrahydro-pyrido [3, 4 - d] pyrimidine compound and its preparation method and application, which belongs to the with anti-tumor activity to the technical field of the synthesis of the compounds. The technical scheme of the present invention is to point: has biological activity of 5, 6, 7, 8 - tetrahydro-pyrido [3, 4 - d] pyrimidine compound, has the following structure:, wherein R1 For the ethyl carboxylic acid ester, ethylamine methyl, formyl methyl amine, dimethyl amino formyl, pyridine - 3 - methylene amino formyl, piperidine a acyl or anilino formyl, R2 For hydrogen or phenmethyl. The invention also discloses the has biological activity of 5, 6, 7, 8 - tetrahydro-pyrido [3, 4 - d] pyrimidine compound of preparation method and the preparation of anti-mammary tumor application of the medicament. The process of preparing the process is simple, easy to control, the target product high yield and good repeatability, prepared with anti-tumor activity of 5, 6, 7, 8 - tetrahydro-pyrido [3, 4 - d] pyrimidine compounds are all on breast cancer cell MCF - 7 has definite inhibitory effect. (by machine translation)

ANTI-ANGIOGENESIS COMPOUND, INTERMEDIATE AND USE THEREOF

Disclosed are an anti-abnormal proliferation of angiogenesis compound represented by formula I, use and intermediate thereof. The compound has good effect against abnormal proliferation of angiogenesis, and the activity of the compound is produced by inhibiting VEGFR2. The compound can be used for treating diseases, such as wet macular degeneration, inflammation, malignant tumor and the like, caused by abnormity of angiogenesis and protein kinases such as VEGFR2, FGFR2 and the like.