40127-11-5

Basic information

• Product Name: L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE
• Synonyms: H-ARG-PNA 2HCL;L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE;L-ARGININE 4-NITROANILIDE DIHYDROBROMIDE;L-ARGININE 4-NITROANILIDE DIHYDROCHLORIDE;H-L-ARG-PNA 2HBR;H-L-ARG-PNA 2HCL;(S)-2-amino-5-guanidino-N-(4-nitrophenyl)pentanamide dihydrobromide;(2S)-2-Amino-5-[(aminoiminomethyl)amino]-N-(4-nitrophenyl)pentanamide dihydrochloride
• CAS NO: 40127-11-5
• Molecular Formula: C₁₂H₁₈N₆O₃*2ClH
• Molecular Weight: 367.23
• Product Categories: Amino Acids;Amino Acids and Derivatives;Activity;Chromogenic;Enzyme Substrates
• Mol File: 40127-11-5.mol

Chemical Properties

• Boiling Point: 621.6oC at 760 mmHg
• Flash Point: 329.8oC
• Appearance: /Solid
• Vapor Pressure: 1.03E-15mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE(40127-11-5)
• EPA Substance Registry System: L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE(40127-11-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 40127-11-5(Hazardous Substances Data)

Usage

Uses

1. Used in Enzyme Research:
L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE is used as a specific substrate for the enzyme cathepsin H, which is involved in various biological processes. This application aids in the study and understanding of the enzyme's function and its role in different cellular activities.
2. Used in Flavor Industry:
L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE is used as a component in the preparation of flavor peptides. These peptides contribute to the enhancement of flavors in the food and beverage industry, providing a richer and more diverse taste experience for consumers.

InChI:InChI=1/C12H18N6O3.ClH/c13-10(2-1-7-16-12(14)15)11(19)17-8-3-5-9(6-4-8)18(20)21;/h3-6,10H,1-2,7,13H2,(H,17,19)(H4,14,15,16);1H/t10-;/m0./s1

Upstream product

• 99306-64-6 N-(t-butoxycarbonyl)-L-arginine p-nitroanilide hydrochloride 
• 134393-23-0 N,N'-bis(4-nitrophenyl)phospheneimidous amide 
• 35897-34-8 N^α-t-butoxycarbonyl-arginine hydrochloride 

Downstream Products

• 125455-61-0 2HCl*H-Gly-Arg-pNA 
• 67508-55-8 N-benzoyl-L-isoleucyl-L-α-glutamylglycyl-N-(4-nitrophenyl)-L-argininamide methyl ester hydrochloride 

Relevant articles and documents

Reinvestigation of the Phosphazo Method and Synthesis of N-(t-Butoxycarbonyl)-L-arginine p-Nitroanilide and a Chromogenic Enzyme Substrate for the Factor Xa

Reaction conditions for the phosphazo method were reinvestigated in order to apply this method to the synthesis of p-nitroanilide(pNA)s of t-butoxycarbonyl(Boc)- and benzyloxycarbonyl(Z)-amino acids.