40171-87-7

Basic information

• Product Name: 2-((4-METHYLBENZYL)AMINO)ETHANOL
• Synonyms: CHEMBRDG-BB 9070464;2-((4-METHYLBENZYL)AMINO)ETHANOL;AKOS LT-968X426;UKRORGSYN-BB BBV-151346;2-[(4-methylbenzyl)amino]ethanol(SALTDATA: HCl)
• CAS NO: 40171-87-7
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• Mol File: 40171-87-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 302.6 °C at 760 mmHg
• Flash Point: 128.7 °C
• Appearance: /
• Density: 1.024 g/cm³
• Vapor Pressure: 0.000432mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: 2-((4-METHYLBENZYL)AMINO)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-METHYLBENZYL)AMINO)ETHANOL(40171-87-7)
• EPA Substance Registry System: 2-((4-METHYLBENZYL)AMINO)ETHANOL(40171-87-7)

Safety Data

• Hazardous Substances Data: 40171-87-7(Hazardous Substances Data)

Usage

General Description

2-((4-Methylbenzyl)amino)ethanol is a chemical compound that contains a benzyl group attached to an amino group and a hydroxyl group. It is an ethanolamine derivative with the chemical formula C10H15NO. 2-((4-METHYLBENZYL)AMINO)ETHANOL is used in the synthesis of various pharmaceuticals, including antihistamines and antipsychotic medications. It also has potential applications in the development of new drugs for treating conditions such as depression, anxiety, and addiction. Additionally, 2-((4-Methylbenzyl)amino)ethanol has properties that make it suitable for use in the production of surfactants, disinfectants, and other specialty chemicals.

InChI:InChI=1/C10H15NO/c1-9-2-4-10(5-3-9)8-11-6-7-12/h2-5,11-12H,6-8H2,1H3

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 141-43-5 ethanolamine 
• 19394-06-0 2-(p-methylbenzylideneamino)ethanol 

Downstream Products

• 3571-00-4 α,α-Dichlor-N-<2-hydroxy-aethyl>-N-<4-methyl-benzyl>-acetamid 
• 115-22-0 3-Hydroxy-3-methyl-2-butanone 
• 1397956-76-1 5-(cyclohexylmethoxy)-3-(((2-hydroxyethyl)(4-methylbenzyl)amino)methyl)-4H-chromen-4-one 
• 73535-69-0 N,N'-bis(p-methylbenzyl)piperazine 

Relevant articles and documents

Ionic liquid-promoted three-component domino reaction of propargyl alcohols, carbon dioxide and 2-aminoethanols: A thermodynamically favorable synthesis of 2-oxazolidinones

To circumvent the thermodynamic limitation of the synthesis of oxazolidinones starting from 2-aminoethanols and CO2 and realize incorporation CO2 under atmospheric pressure, a protic ionic liquid-facilitated three-component reaction of propargyl alcohols, CO2 and 2-aminoethanols was developed to produce 2-oxazolidinones along with equal amount of α-hydroxyl ketones. The ionic liquid structure, reaction temperature and reaction time were in detail investigated. And 15 mol% 1,5,7-triazabicylo[4.4.0]dec-5-ene ([TBDH][TFE]) trifluoroethanol was found to be able to synergistically activate the substrate and CO2, thus catalyzing this cascade reaction under atmospheric CO2 pressure. By employing this task-specific ionic liquid as sustainable catalyst, 2-aminoethanols with different substituents were successfully transformed to 2-oxazolidinones with moderate to excellent yield after 12 h at 80 °C.

Triazole Derivatives, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same

The present invention refers to view body prostaglandin E 2 synthase -1 (mPGES-1) inhibitors having excellent effects of triazole derivatives, including as an active ingredient and manufacturing method thereof pharmaceutical composition is disc