40235-65-2 Usage
General Description
Ethyl 2-(hydroxyMethyl)thiazole-4-carboxylate is a chemical compound with the molecular formula C8H11NO3S. It is a synthetic organic compound used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It belongs to the thiazole class of compounds and contains a thiazole ring with an ethyl ester side chain. Ethyl 2-(hydroxyMethyl)thiazole-4-carboxylate has potential therapeutic properties and may be used in the development of new medications. It is important to handle and store this chemical with care, as it can be hazardous if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 40235-65-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,2,3 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40235-65:
(7*4)+(6*0)+(5*2)+(4*3)+(3*5)+(2*6)+(1*5)=82
82 % 10 = 2
So 40235-65-2 is a valid CAS Registry Number.
40235-65-2Relevant articles and documents
Structure elucidation of colibactin and its DNA cross-links
Xue, Mengzhao,Kim, Chung Sub,Healy, Alan R.,Wernke, Kevin M.,Wang, Zhixun,Frischling, Madeline C.,Shine, Emilee E.,Wang, Weiwei,Herzon, Seth B.,Crawford, Jason M.
, (2019/09/16)
Colibactin is a complex secondary metabolite produced by some genotoxic gut Escherichia coli strains. The presence of colibactin-producing bacteria correlates with the frequency and severity of colorectal cancer in humans. However, because colibactin has not been isolated or structurally characterized, studying the physiological effects of colibactin-producing bacteria in the human gut has been difficult. We used a combination of genetics, isotope labeling, tandem mass spectrometry, and chemical synthesis to deduce the structure of colibactin. Our structural assignment accounts for all known biosynthetic and cell biology data and suggests roles for the final unaccounted enzymes in the colibactin gene cluster.