40235-78-7

Basic information

• Product Name: 2-keto-4-methyl-3H-thiazole-5-carboxylic acid ethyl ester
• Synonyms: 2-keto-4-methyl-3H-thiazole-5-carboxylic acid ethyl ester;4-methyl-2-oxo-3H-thiazole-5-carboxylic acid ethyl ester;ethyl 4-methyl-2-oxo-2,3-dihydro-1,3-thiazole-5-carboxylate;ethyl 4-methyl-2-oxo-2,3-dihydrothiazole-5-carboxylate;ethyl 4-methyl-2-oxo-3H-1,3-thiazole-5-carboxylate;ethyl 4-methyl-2-oxo-3H-thiazole-5-carboxylate;Ethyl 2-hydroxy-4-methyl-1,3-thiazole-5-carboxylate
• CAS NO: 40235-78-7
• Molecular Formula: C₇H₉NO₃S
• Molecular Weight: 187.22
• Mol File: 40235-78-7.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-keto-4-methyl-3H-thiazole-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-keto-4-methyl-3H-thiazole-5-carboxylic acid ethyl ester(40235-78-7)
• EPA Substance Registry System: 2-keto-4-methyl-3H-thiazole-5-carboxylic acid ethyl ester(40235-78-7)

Safety Data

• Hazardous Substances Data: 40235-78-7(Hazardous Substances Data)

Upstream product

• 7238-62-2 ethyl 2-chloro-4-methylthiazole-5-carboxylate 
• 626-34-6 ethyl aminocrotonate 
• 2757-23-5 chloro(chlorosulfanyl)methanone 
• 16687-42-6 ammonium thiocarbamate 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 156498-55-4 ethyl N-acetyl-5-methyl-1,3-oxathiol-2-imine-4-carboxylate 
• 626-34-6 ethyl 3-aminobut-2-enoate 
• 65573-12-8 4-chloro-5H-1,2,3-dithiazole-5-one 
• 637-98-9 S-ethyl thiocarbamate 
• 13176-46-0 4-bromoethyl acetoacetate 

Downstream Products

• 7238-62-2 ethyl 2-chloro-4-methylthiazole-5-carboxylate 
• 1400661-12-2 2-[3-(3-Methoxy-phenyl)-propoxy]-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 1400661-13-3 2-[3-(3-Hydroxy-phenyl)-propoxy]-4-methyl-thiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

AMINOPHENYLCYCLOPROPYL CARBOXYLIC ACIDS AND DERIVATIVES AS AGONISTS TO GPR40

The present invention relates generally to novel therapeutic compounds and more particularly to novel compounds, their use as GPR40 agonists, processes for their manufacture, and intermediates useful in their preparation.

Pyrazolecarboxylic acid derivatives and plant disease control agent

The present invention provides a plant disease control agent containing as active ingredient one or more compounds of the formula [1]A--COOR 1 [1]whereinR 1 represents a hydrogen atom or a C 1 -C 4 alkyl group, andA represents a group of the formula (A-1) or (A-2) STR1 R 2 represents a C 1 -C 4 alkyl group, R 3 represents a C 1 -C 4 alkyl group,R 4 represents a halogen atom or a C 1 -C 4 alkyl group, andR 5 represents a C 1 -C 4 alkyl group.Further, the compound of A-1 in the formula [1] in which R 3 is a halogen atom is also included in the present invention.

Synthesis of Heterocyclic Compounds from 0-Aminobenzenethiol and Ammonium Thiocarbamate

The reaction of o-aminobenzenethiol with carbonyl sulfide in the presence of triethylamine afforded an alternate route for the synthesis of 2-benzothiazolinone (1) in 97-98percent yield.The reaction of ammonium thiocarbamate (2) with 2-chlorocyclohexanone furnished the novel 4,5,6,7-tetrahydro-2-benzothiazolinone (3). 3-Ethoxy-2H-1,4-benzothiazin-2-one (7) was prepared by the reaction of o-aminobenzenethiol with diethyl oxalate.Possible pathways and supporting nmr, ir and mass spectra are discussed.