405-99-2

Basic information

• Product Name: 4-Fluorostyrene
• Synonyms: P-FLUOROSTYRENE;1-fluoro-4-ethenylbenzene;1-Fluoro-4-vinylbenzene;para-Fluorostyrene;Styrene, p-fluoro-;4-Fluorostyrene, 97+%;4-Fluorostyrene,98+%;4-Fluorostyrene, stabilized, 97%
• CAS NO: 405-99-2
• Molecular Formula: C₈H₇F
• Molecular Weight: 122.14
• EINECS: 206-975-0
• Product Categories: Styrenes;monomer;Monomers;Polymer Science;Styrene and Functionalized Styrene Monomers;Fluorine series
• Mol File: 405-99-2.mol
• Article Data: 108

Chemical Properties

• Melting Point: -36--33°C
• Boiling Point: 67 °C50 mm Hg(lit.)
• Flash Point: 80 °F
• Appearance: Clear colorless to very slightly yellow/Liquid
• Density: 1.024 g/mL at 25 °C(lit.)
• Vapor Pressure: 6.17mmHg at 25°C
• Refractive Index: n20/D 1.514(lit.)
• Storage Temp.: 2-8°C
• Water Solubility: Insoluble in water.
• BRN: 1634203
• CAS DataBase Reference: 4-Fluorostyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluorostyrene(405-99-2)
• EPA Substance Registry System: 4-Fluorostyrene(405-99-2)

Safety Data

• Hazard Codes: F,Xi
• Statements: 10-36/37/38
• Safety Statements: 23-24/25-37/39-26-16
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 405-99-2(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to very slightly yellow liquid

Uses

4-Fluorostyrene, is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

InChI:InChI=1/C8H7F/c1-2-7-3-5-8(9)6-4-7/h2-6H,1H2

Upstream product

• 332-42-3 (2-bromoethyl)-4-fluorobenzene 
• 7589-27-7 2-(4-Fluorophenyl)ethanol 
• 456-16-6 1-(1-chloroethyl)-4-fluorobenzene 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 18511-62-1 4-fluorostyrene oxide 
• 593-60-2 Vinyl bromide 
• 1765-93-1 4-fluoroboronic acid 
• 352-34-1 4-fluoro-1-iodobenzene 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 2343-30-8 1-fluoro-4-(2-fluoroethyl)benzene 
• 84648-18-0 C₁₆H₁₂ClFO₄ 
• 3020-28-8 (iodomethyl)triphenylphosphonium iodide 

Downstream Products

• 350-35-6 1-(1,2-dibromoethyl)-4-fluorobenzene 
• 1580-83-2 paraflutizide 
• 18511-60-9 4-fluoro-1-cyclopropyl-benzene 
• 14331-42-1 6-bromo-3-(4-fluoro-benzyl)-1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide 
• 20968-47-2 p-(2,2-Dichlorocyclopropyl)fluorobenzene 
• 64-19-7 acetic acid 
• 109764-64-9 1,10-Dibrom<2.2>paracyclophan-1-en 
• 109764-63-8 1,9-Dibrom<2.2>paracyclophan-1-en 
• 109764-92-3 4'',5'-Bis(4-fluorphenyl)dibenzo<2.2>paracyclophan-1,9-dien-4',5''-dicarbaldehyd 
• 109764-93-4 5',5''-Bis(4-fluorphenyl)dibenzo<2.2>paracyclophan-1,9-dien-4,4''-dicarbaldehyd 
• 109764-88-7 C₃₈H₂₆F₂O₂ 
• 109764-89-8 C₃₈H₂₆F₂O₂ 
• 263-06-9 6H,12H-Dibenzo<1,5>dithiocin 
• 120229-48-3 3-(4-Fluorphenyl)-3,4-Dihydro-2H-1-benzothiopyran 

Relevant articles and documents

Vinyl Thianthrenium Tetrafluoroborate: A Practical and Versatile Vinylating Reagent Made from Ethylene

The use of vinyl electrophiles in synthesis has been hampered by the lack of access to a suitable reagent that is practical and of appropriate reactivity. In this work we introduce a vinyl thianthrenium salt as an effective vinylating reagent. The bench-stable, crystalline reagent can be readily prepared from ethylene gas at atmospheric pressure in one step and is broadly useful in the annulation chemistry of (hetero)cycles, N-vinylation of heterocyclic compounds, and palladium-catalyzed cross-coupling reactions. The structural features of the thianthrene core enable a distinct synthesis and reactivity profile, unprecedented for other vinyl sulfonium derivatives.

Mild and efficient desulfurization of thiiranes with MoCl5/Zn system

Desulfurization of a variety of thiiranes to alkenes occurs chemoselectively in high yields upon treatment with MoCl5/Zn system under mild conditions. The new methodology demonstrates high functional group tolerance toward chloro, bromo, fluoro, methoxy, ester, ether and keto groups.

Controlling the Lewis Acidity and Polymerizing Effectively Prevent Frustrated Lewis Pairs from Deactivation in the Hydrogenation of Terminal Alkynes

Two strategies were reported to prevent the deactivation of Frustrated Lewis pairs (FLPs) in the hydrogenation of terminal alkynes: reducing the Lewis acidity and polymerizing the Lewis acid. A polymeric Lewis acid (P-BPh3) with high stability was designed and synthesized. Excellent conversion (up to 99%) and selectivity can be achieved in the hydrogenation of terminal alkynes catalyzed by P-BPh3. This catalytic system works quite well for different substrates. In addition, the P-BPh3 can be easily recycled.