409081-78-3

Basic information

• Product Name: 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl} acetic acid
• Synonyms: 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl} acetic acid
• CAS NO: 409081-78-3
• Molecular Weight: 343.733
• Mol File: 409081-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl} acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl} acetic acid(409081-78-3)
• EPA Substance Registry System: 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl} acetic acid(409081-78-3)

Safety Data

• Hazardous Substances Data: 409081-78-3(Hazardous Substances Data)

Downstream Products

• 409081-82-9 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl}-N-({6-[(tert-butoxy)carbonylamino]-2,4-dimethyl(3-pyridyl)}methyl) acetamide 
• 409081-81-8 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl}-N-({6-[(tert-butoxy)carbonylamino]-2-methyl(3-pyridyl)}methyl) acetamide 

Relevant articles and documents

2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors

2-(2-Chloro-6-fluorophenyl)acetamides having 2,2-difluoro-2-aryl/heteroaryl-ethylamine P3 and oxyguanidine P1 substituents are potent thrombin inhibitors (Ki = 0.9-33.9 nM). 2-(5-Chloro-pyridin-2-yl)-2,2-difluoroethylamine was the best P3 subst