4094-37-5

Basic information

• Product Name: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-
• CAS NO: 4094-37-5
• Molecular Formula: C13H11NO4S
• Molecular Weight: 277.301
• Mol File: 4094-37-5.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-(4094-37-5)
• EPA Substance Registry System: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfonyl]-(4094-37-5)

Safety Data

• Hazardous Substances Data: 4094-37-5(Hazardous Substances Data)

Upstream product

• 100-25-4 para-dinitrobenzene 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 636-98-6 p-nitrobenzene iodide 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 100-01-6 4-nitro-aniline 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 98-59-9 p-toluenesulfonyl chloride 
• 624-31-7 4-tolyl iodide 
• 3729-43-9 Allyl 4-nitrophenyl sulfone 
• 586-78-7 para-nitrophenyl bromide 
• 100-02-7 4-nitro-phenol 
• 100-00-5 4-chlorobenzonitrile 
• 10486-08-5 sodium p-thiocresolate 
• 17763-80-3 para-nitrophenyl triflate 

Downstream Products

• 100-02-7 4-nitro-phenol 
• 104-15-4 toluene-4-sulfonic acid 
• 103649-37-2 4-[4-(4-nitro-benzenesulfonyl)-benzylamino]-benzoic acid 
• 102003-25-8 4-[4-(4-amino-benzenesulfonyl)-benzylamino]-benzoic acid 
• 102881-61-8 dimethyl-[4-(4-nitro-benzenesulfonyl)-benzyl]-amine 
• 4393-17-3 4-(4-nitro-benzenesulfonyl)-benzylamine 
• 100958-01-8 dimethyl-(4-sulfanilyl-benzyl)-amine 
• 4393-19-5 p-sulfanilylbenzylamine 
• 859491-77-3 toluene-4-sulfonic acid-[4-(toluene-4-sulfonyl)-anilide] 
• 138384-83-5 (2-Imino-5-methyl-1,2-dihydro-benzo[cd]indol-6-yl)-methyl-[4-(4-nitro-benzenesulfonyl)-benzyl]-amine 
• 138384-81-3 5-Methyl-6-{methyl-[4-(4-nitro-benzenesulfonyl)-benzyl]-amino}-1H-benzo[cd]indol-2-one 
• 138384-67-5 6-{Methyl-[4-(4-nitro-benzenesulfonyl)-benzyl]-amino}-1H-benzo[cd]indol-2-one 
• 293758-44-8 2-methyl-5-(4-nitro-benzenesulfonyl)-benzenesulfonyl chloride 
• 32682-56-7 3,4,5-triphenyl-2-benzoylfuran 

Relevant articles and documents

Visible-light-driven electron donor-acceptor complex induced sulfonylation of diazonium salts with sulfinates

This work reports an efficient sulfonylation reaction enabled by a visible-light-induced radical coupling reaction between phenyl/heterocyclic diazonium salts and sulfinates. Mechanistic experiments disclosed the formation of a versatile electron donor-acceptor (EDA) complex. This transformation is characterized by an easy operational procedure under mild conditions which avoids transition metals, ligands, catalysts, and oxidants.

Mo(VI) complex catalysed synthesis of sulfonees and their modification for anti-HIV activities

An efficient method for the synthesis of sulfones has been developed using sugar derived cis-dioxo molybdenum(VI) complex as catalyst and urea hydrogen peroxide as oxygen source. Present method is highly specific for sulfide oxidation irrespective of presence of alkene and aldehyde groups in the same molecule. Synthesis of fifteen sulfones have been reported with 82–98% isolated yields and the catalyst has been reused five times without any loss in its activity. 2-(Phenylsulfonyl)aniline has been condensed with eight different aromatic aldehydes and the products are being explored for HIV-1 reverse transcriptase inhibition activities.

Nano copper catalyzed synthesis of symmetrical/unsymmetrical sulfones from aryl/alkyl halides and p-toluenesulfonylmethylisocyanide: TosMIC as a tosyl source

A magnetically induced nano copper-catalyzed efficient and mild route for the synthesis of diaryl and alkyl/aryl sulfones from aryl/alkyl halides and tosylmethyl isocyanide (TosMIC) has been developed. A variety of aryl and alkyl sulfones have been obtained in very good to excellent yields. Sulfones containing molecules have medicinal relevance as they are known to possess various activities such as antifungal, anti-HIV, antitumor, and anticancer. Herein, a magnetically induced nano copper-catalyzed efficient and mild route for the synthesis of biaryl and alkyl/aryl sulfones from aryl/alkyl halides and tosylmethyl isocyanide (TosMIC) has been developed. A variety of aryl and alkyl sulfones have been obtained in very good to excellent yields. In this newly developed protocol TosMIC acts as sulfonyl source. The catalyst can magnetically be recovered and recycled five times without significant loss in activity.