422-61-7

Basic information

• Product Name: PENTAFLUOROPROPIONYL FLUORIDE
• Synonyms: pentafluoro-propanoylfluorid;Perfluoropropionyl fluoride;Propanoyl fluoride, pentafluoro-;PENTAFLUOROPROPIONYL FLUORIDE;Pentafluoropropionyl fluoride 97%;Pentafluoropropionylfluoride97%;1,2,2,3,3,3-Hexafluoro-1-propanone;2,2,3,3,3-Pentafluoropropionic acid fluoride
• CAS NO: 422-61-7
• Molecular Formula: C₃F₆O
• Molecular Weight: 166.02
• EINECS: 207-019-5
• Mol File: 422-61-7.mol
• Article Data: 39

Chemical Properties

• Boiling Point: -30°C
• Flash Point: °C
• Appearance: /
• Density: 1.537g/cm³
• Vapor Pressure: 1560mmHg at 25°C
• Refractive Index: 1.247
• CAS DataBase Reference: PENTAFLUOROPROPIONYL FLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: PENTAFLUOROPROPIONYL FLUORIDE(422-61-7)
• EPA Substance Registry System: PENTAFLUOROPROPIONYL FLUORIDE(422-61-7)

Safety Data

• Hazard Codes: C,T
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3308
• HazardClass: GAS, TOXIC, CORROSIVE
• Hazardous Substances Data: 422-61-7(Hazardous Substances Data)

Usage

Uses

Pentafluoropropionyl Fluoride is used as a reagent in the synthesis of perfluoroallyl fluorosulfate (FAFS) as a building block for fluoroallylic compounds.

Safety Profile

May explode on contact with fluorinated catalysts. When heated to decomposition it emits toxic fumes of Fí.

InChI:InChI=1/C3F6O/c4-1(10)2(5,6)3(7,8)9

Upstream product

• 3853-06-3 methyl 3-(dimethylamino)propionate 
• 13330-96-6 4-dimethylamino-1-butanol 
• 116-14-3 polytetrafluoroethylene 
• 353-50-4 Carbonyl fluoride 
• 802294-64-0 propionic acid 
• 2062-98-8 perfluoro(2-propoxypropionyl) fluoride 
• 2641-34-1 perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride 
• 422-59-3 2,2,3,3,3-pentafluoropropionyl chloride 
• 428-59-1 Hexafluoropropene oxide 
• 116-15-4 perfluoropropylene 
• 141-75-3 butyryl chloride 
• 79-03-8 propionyl chloride 
• 423-41-6 perfluoropropanesulfonic acid 
• 11113-87-4 silver fluoride 

Downstream Products

• 354-64-3 Pentafluoroethyl iodide 
• 6129-62-0 2,3,3,3-tetrafluoro-2-bromopropanoyl fluoride 
• 28627-00-1 2,3,3,3-tetrafluoro-2-chloropropanoyl fluoride 
• 73602-61-6 triethylamine tris(hydrogen fluoride) 
• 137741-03-8 Perfluoropropionyliodid 
• 64609-91-2 Pentafluor-propionylbromid 
• 76-14-2 1,2-dichloro-1,1,2,2-tetrafluoroethane 
• 106372-30-9 perfluoropropyl 1,2-Dichlorotrifluoroethyl Ether 
• 354-25-6 2-chloro-1,1,2,2-tetrafluoroethane 
• 75995-75-4 1,4-dichloro-1,1,2,3,4,4-hexafluorobutane 
• 422-64-0 pentafluoropropionic acid 
• 756-13-8 perfluoro-2-methylpentan-3-one 
• 684-32-2 perfluoro-3-pentanone 
• 378-75-6 perfluoropropionic acid methyl ester 

Relevant articles and documents

Electrochemical fluorination of N,N-dimethylperfluoroacylamides

The electrochemical fluorination (ECF) of N,N-dimethylperfluoroacylamides gives the corresponding perfluoro-N,N-dimethylacylamides in low yield. With increase of the number of carbon atoms in the perfluoroacyl radical the yield of the required perfluoro-N

Trifluoromethyl Benzoate: A Versatile Trifluoromethoxylation Reagent

Trifluoromethyl benzoate (TFBz) is developed as a new shelf-stable trifluoromethoxylation reagent, which can be easily prepared from inexpensive starting materials using KF as the only fluorine source. The synthetic potency of TFBz is demonstrated by trifluoromethoxylation-halogenation of arynes, nucleophilic substitution of alkyl (pseudo)halides, cross-coupling with aryl stannanes, and asymmetric difunctionalization of alkenes. The unprecedented trifluoromethoxylation-halogenation of arynes proceeds smoothly at room temperature with the aid of a crown ether-complexed potassium cation, which significantly stabilizes the trifluoromethoxide anion derived from TFBz.

Preparation method of perfluoronitrile

The invention discloses a preparation method of perfluoronitrile. The preparation method comprises the following steps: a, performing a gas-phase addition reaction on perfluoroolefin R1R2C=CR3R4 and carbonyl fluoride to obtain acyl fluoride R1R2(COF)C-CFR3R4 (R1, R2, R3 and R4 have a general formula of a -CnF2n+1 group and n is a nonnegative integer set); b, aminating and dehydrating the acyl fluoride R1R2(COF)C-CFR3R4, acyl fluoride and alkali metal amide or an amine compound R-NH2 (R is lithium, sodium, potassium, rubidium, cesium or a -CmH2m+1 group and m is a nonnegative integer set) to obtain the perfluoronitrile R1R2(CN)C-CFR3R4. By the preparation method, a reaction route is short, the perfluoroolefin and the carbonyl fluoride are easy to obtain and low in price, the overall yield of the perfluoronitrile is high and the route is easy to industrialize.

One stone two birds: Degradation of persistent organic pollutants to a valuable industrial chemical production of pentafluoropropionyl fluoride from HFPO oligomers catalyzed by cesium fluoride in tetraglyme

Hexafluoropropylene oxide (HFPO) oligomers are toxic, bioaccumulative, and persistent organic pollutants (POPs). Consuming the harmful chemicals to prevent them from releasing to nature is of serious significance as far as both natural environments and human health are concerned. In this study, investigation on degradation of HFPO oligomers to pentafluoropropionyl fluoride (PPF), a valuable industrial chemical, is reported. Different combinations of alkali metal fluoride in either diglyme or tetraglyme under both flask and batch autoclave conditions were examined. Under the optimal reaction conditions, HFPO oligomers (n?=?2–10) were completely degraded to PPF in over 90% yield. Reactions on 200?g scale were tested and no deduction of efficiency was observed, which indicates the potential for practical industrial application of this chemistry.