424-40-8

Basic information

• Product Name: DIETHYL HEXAFLUOROGLUTARATE
• Synonyms: 2,2,3,3,4,4-HEXAFLUOROPENTANEDIOIC ACID DIETHYL ESTER;DIETHYL HEXAFLUOROGLUTARATE;DIETHYL 2,2,3,3,4,4-HEXAFLUOROPENTANEDIOATE;HEXAFLUOROGLUTARIC ACID DIETHYL ESTER;Diethyl perfluoroglutarate;Diethylester kyseliny hexafluorglutarove;diethylesterkyselinyhexafluorglutarove;diethylhexafluoropentanedioate
• CAS NO: 424-40-8
• Molecular Formula: C₉H₁₀F₆O₄
• Molecular Weight: 296.16
• EINECS: 207-035-2
• Mol File: 424-40-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 75 °C
• Flash Point: 76-79°C/3mm
• Appearance: /
• Density: 1.344
• Vapor Pressure: 0.0935mmHg at 25°C
• Refractive Index: 1.3599
• BRN: 1804802
• CAS DataBase Reference: DIETHYL HEXAFLUOROGLUTARATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL HEXAFLUOROGLUTARATE(424-40-8)
• EPA Substance Registry System: DIETHYL HEXAFLUOROGLUTARATE(424-40-8)

Safety Data

• Hazard Codes: C
• Statements: 36/37/38
• Safety Statements: 26-36
• RTECS: MA3750500
• TSCA: Yes
• HazardClass: CORROSIVE
• Hazardous Substances Data: 424-40-8(Hazardous Substances Data)

Usage

Uses

Diethyl Hexafluoroglutarate can be used for oil production process for selective water plugging method of oil wells.

InChI:InChI=1/C9H10F6O4/c1-3-18-5(16)7(10,11)9(14,15)8(12,13)6(17)19-4-2/h3-4H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 376-73-8 hexafluoroglutaric acid 
• 714-37-4 nonafluoro-2,3,4,5-tetrahydropyridine 
• 2375-90-8 4-methoxy-2,3,5,6-tetrafluoropyridine 
• 836-77-1 perfluoro-N-fluoropiperidine 
• 110-86-1 pyridine 
• 110-89-4 piperidine 
• 700-16-3 Pentafluoropyridine 
• 1001383-52-3 diethyl 2,2,4,4,-tetrafluoro-3-oxopentanedioate 

Downstream Products

• 376-90-9 2,2,3,3,4,4-hexafluoro-1,5-pentanediol 
• 376-89-6 hexafluoro-glutaronitrile 
• 507-68-6 hexafluoroglutaramide 
• 94219-87-1 3,3,4,4,5,5-Hexafluoro-1,7-diphenyl-heptane-1,2,6,7-tetraone 
• 58191-56-3 C₁₇H₁₀F₆N₈O₈ 
• 154566-75-3 1,2-bis(5'-formyl-2'-methylthien-3'-yl)perfluorocyclopentene 
• 2525-83-9 2,2,3,3,4,4-hexafluoro-1,5-diphenylpentane-1,5-dione 
• 94219-86-0 1,1,7,7-Tetrachloro-3,3,4,4,5,5-hexafluoro-1,7-diphenyl-heptane-2,6-dione 

Relevant articles and documents

Conformational characteristics of aliphatic diesters derived from fluorinated diacids

A comparative study of the polarity and conformational characteristics of diethyl hexafluoroglutarate (DEFG) and its hydrogenated diester counterpart, diethyl glutarate (DEG), is reported. The value at 30°C of the mean-square dipole moment 〈μ2〉 of the latter compound, 5.26 D2, is nearly 2 times larger the value of this quantity for the fluorinated diester, which amounts to 12.1 D2 at the same temperature. Values of the conformational energies associated with the rotational states about the skeletal bonds of the acid residue were calculated by combining molecular mechanics with the critical interpretation of the mean-square dipole moment of these compounds, finding that the rotational populations about the different skeletal bonds are similar in both molecules. The evaluation of 〈μ2〉 as a function of the conformational energies indicates that the experimental results are reproduced assuming that the conformation in which the C=O* group eclipses the Cα-Cβ bond in the CβCαC*(O*)O residue is less stable than the alternative conformation in which the carbonyl group eclipses the Cα-F (or Cα- H) bond. The analysis suggests that the high polarity exhibited by DEFG, in comparison with that of DEG, arises from differences in the orientation and the modulus of the dipoles in both compounds rather than from differences in their conformational characteristics.

Biphenyl-pyrazolecarboxamide compounds

The present invention relates to biphenyl-pyrazole compounds and in particular biphenyl-pyrazolecarboxamides. The invention further provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by antagonism or inverse agonism of the CB1 receptor, such as obesity, smoking cessation, and normalization of blood lipid composition.