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All total 10 Articles be found
All total 10 Articles be foundDual signaling of thallium(III) ions via oxidative cleavage of a sulfonhydrazide linkage
Ahn, Sangdoo,Chang, Suk-Kyu,Choi, Myung Gil,Lee, Yu Jeong,Park, Tae Jung,Yoo, Jae Hoon
, (2020/03/17)
The thallium is widely used in various research and industrial applications but is very toxic. In this work, we developed a novel reaction-based dual signaling probe for the selective and sensitive determination of Tl3+ via the oxidative cleavage of a rhodamine–dansylhydrazide conjugate. The designed probe showed pronounced colorimetric and fluorescence signaling behavior toward Tl3+ with a detection limit of 1.3 × 10–7 M (0.027 ppm), as well as selectivity over other common metal ions, anions, and oxidants. The Tl3+ signaling process required less than 2 min and was not influenced by the solution pH within the range of 4.0–5.5; however, the signal diminished significantly above pH 6.0. To demonstrate the practical applicability of the designed probe, a simple and convenient colorimetric assay for the determination of Tl3+ in commercial reagents was established using an office scanner as a readily available signal capturing device.
Synthetic method of dansyl chloride for preparing fluorescent probe (by machine translation)
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Paragraph 0029-0035, (2020/07/14)
The preparation method comprises the following steps: dissolving rhodamine sulfonic acid in an organic solvent to obtain an emulsion; sequentially dropwise adding thionyl chloride and phosphorus pentachloride into the suspension; controlling the temperature of the system to 40 - 45 °C; reacting 4 - 6h; adjusting pH to 5 - 6; and collecting the product to obtain the folic acid chloride. The invention further discloses a fluorescent probe prepared from the dansyl chloride. In the synthesis process of the target fluorescent compound, by adding the phosphorus pentachloride catalyst, the use amount of thionyl chloride is reduced, the reaction condition is mild, and the method can be carried out at a lower temperature. (by machine translation)
Preparation method of 6-deuterated dansyl chloride
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Paragraph 0076-0078, (2020/12/14)
The invention belongs to the technical field of isotope derivatization reagent preparation, and particularly relates to a preparation method of 6-deuterated dansyl chloride. According to the preparation method, 6-deuterated dansyl chloride can be prepared from reaction raw materials including 5-amino-1-naphthalene sulfonic acid, sodium hydride, deuterated methyl iodide, phosphorus oxychloride andphosphorus pentachloride. The preparation method has the advantages of easily available raw materials, low toxicity, few intermediate products and high yield.
A N-(2-aminophenyl)-5-(dimethylamino)-1-naphthalenesulfonic amide (Ds-DAB) based fluorescent chemosensor for peroxynitrite
Lin, Ku-Kuei,Wu, Shou-Cheng,Hsu, Kuang-Mei,Hung, Chen-Hsiung,Liaw, Wen-Feng,Wang, Yun-Ming
supporting information, p. 4242 - 4245 (2013/09/12)
A dansyl derivative (Ds-DAB) was prepared and used as a fluorescent probe for peroxynitrite (ONOO-) detection. The results showed that the addition of peroxynitrite to the aqueous solution of Ds-DAB would result in obvious fluorescence enhancem
A trifluoroacetic acid-labile sulfonate protecting group and its use in the synthesis of a near-IR fluorophore
Pauff, Steven M.,Miller, Stephen C.
supporting information, p. 711 - 716 (2013/02/25)
Sulfonated molecules exhibit high water solubility, a property that is valuable for many biological applications but often complicates their synthesis and purification. Here we report a sulfonate protecting group that is resistant to nucleophilic attack but readily removed with trifluoroacetic acid (TFA). The use of this protecting group improved the synthesis of a sulfonated near-IR fluorophore and the mild deprotection conditions allowed isolation of the product without requiring chromatography.
