438248-78-3

Basic information

• Product Name: N-[4-Methyl-3-(2-pyridin-4-yl-6-(trifluoromethyl)pyrimidin-4-ylamino)-phenyl]-4-morpholino-benzamide
• CAS NO: 438248-78-3
• Molecular Weight: 534.541
• Mol File: 438248-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[4-Methyl-3-(2-pyridin-4-yl-6-(trifluoromethyl)pyrimidin-4-ylamino)-phenyl]-4-morpholino-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-Methyl-3-(2-pyridin-4-yl-6-(trifluoromethyl)pyrimidin-4-ylamino)-phenyl]-4-morpholino-benzamide(438248-78-3)
• EPA Substance Registry System: N-[4-Methyl-3-(2-pyridin-4-yl-6-(trifluoromethyl)pyrimidin-4-ylamino)-phenyl]-4-morpholino-benzamide(438248-78-3)

Safety Data

• Hazardous Substances Data: 438248-78-3(Hazardous Substances Data)

Upstream product

• 438248-72-7 4-(5-amino-2-methylanilino)-2-(4-pyridinyl)-6-(trifluoromethyl)pyrimidine 
• 7470-38-4 4-morpholin-4-yl-benzoic acid 

Relevant articles and documents

Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 2-aryl-4-arylaminopyrimidine and analogs thereof, represented by the general Formula I: wherein A, Ar1, Ar2, R1 and R3 are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. The compounds of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.