4545-84-0

Basic information

• Product Name: dimethyl bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylate
• Synonyms: Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid, dimethyl ester; Dimethyl bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylate
• CAS NO: 4545-84-0
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.253
• Mol File: 4545-84-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 303.1°C at 760 mmHg
• Flash Point: 146.2°C
• Density: 1.171g/cm³
• Vapor Pressure: 0.000952mmHg at 25°C
• Refractive Index: 1.501
• CAS DataBase Reference: dimethyl bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylate(4545-84-0)
• EPA Substance Registry System: dimethyl bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylate(4545-84-0)

Safety Data

• Hazardous Substances Data: 4545-84-0(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 24327-08-0 meso-endo-tetrahydro-4,7-ethanoisobenzofuran-1,3-dione 
• 67-56-1 methanol 
• 84258-03-7 trans-2,3-bis(chloroformyl)bicyclo<2.2.2>oct-5-ene 
• 84258-03-7 trans-Bicyclo<2.2.2>octen-(5)-2,3-dicarboxychlorid 
• 56787-64-5 bicyclo<2.2.2>oct-5-ene-trans-2,3-dicarboxylic acid exo-3-methyl ester 
• 28871-80-9 bicyclo<2.2.2>oct-5-ene 2,3-endo,exo-dicarboxylic acid 
• 1165952-91-9 cyclohexa-1,3-diene 
• 624-49-7 dimethylfumarate 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 

Downstream Products

• 72443-96-0 methyl (2SR,10RS)-2-(phenylseleno)-4-oxa-5-oxotricyclo<4.3.1.0^3,7>decane-10-carboxylate 
• 72443-95-9 methyl (2SR,7RS)-2-(phenylseleno)-4-oxa-5-oxotricyclo<4.4.0.0^3,8>decane-7-carboxylate 
• 72443-97-1 dimethyl (2SR,3RS,5SR,6RS)-2-(phenylseleno)-3-chloro-bicyclo<2.2.2>octane-5,6-dicarboxylate 
• 72496-17-4 dimethyl (2SR,3SR,5SR,6RS)-2-(phenylseleno)-3-chlorobicyclo<2.2.2>octane-5,6-dicarboxylate 
• 72444-15-6 methyl (2SR,10RS)-2-<(2-methyl-4-nitrophenyl)thio>-4-oxatricyclo<4.3.1.0^3,7>deca-5-one-10-carboxylate 
• 72453-32-8 methyl (2SR,7RS)-2-<(2-methyl-4-nitrophenyl)thio>-4-oxa-5-oxotricyclo<4.4.0.0^3,8>decane-7-carboxylate 
• 4545-84-0 dimethyl bicyclo<2,2,2>oct-5-ene-endo-2,exo-3-dicarboxylate 
• 72444-10-1 methyl (2SR,10RS)-2-<(2,4-dinitrophenyl)thio>-4-oxatricyclo<4.3.1.0^3,7>deca-5-one-10-carboxylate 
• 72453-31-7 methyl (2SR,7RS)-2-<(2,4-dinitrophenyl)thio>-4-oxa-5-oxotricyclo<4.4.0.0^3,8>decane-7-carboxylate 
• 54290-45-8 bis p-toluenesulfonate of trans-2,3-bis(hydroxymethyl)bicyclo<2.2.2>oct-5-ene 
• 72444-12-3 methyl (2SR,10RS)-2-<(2-nitrophenyl)thio>-4-oxatricyclo<4.3.1.0^3,7>deca-5-one-10-carboxylate 
• 72444-07-6 methyl (2SR,7RS)-2-<(2-nitrophenyl)thio>-4-oxa-5-oxotricyclo<4.4.0.0^3,8>decane-7-carboxylate 
• 72444-11-2 methyl (2SR,10RS)-2-<(4-chloro-2-nitrophenyl)thio>-4-oxatricyclo<4.3.1.0^3,7>deca-5-one-10-carboxylate 
• 72444-06-5 methyl (2SR,7RS)-2-<(4-chloro-2-nitrophenyl)thio>-4-oxa-5-oxotricyclo<4.4.0.0^3,8>decane-7-carboxylate 

Relevant articles and documents

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Deuterium Kinetic Isotope Effects in the 1,4-Dimethylenecyclohexane Boat Cope Rearrangement

In order to examine the extent of bond making in the boat-like 3,3-sigmatropic shift transition states, trans-2,3-dimethyl-1,4-dimethylenecyclohexane (T) and its exomethylene tetradeuteria derivative (TXD) were prepared.The 3,3-shift of TXD at 305 deg C r

Additions of Group 6A and 7A Electrophilic Reagents to Dimethyl endo,endo-Bicyclooct-5-ene-2,3-dicarboxylate: Competitive Formation of γ- and δ-Lactones

The reaction of dimethyl endo,endo-bicyclooct-5-ene-2,3-dicarboxylate with chlorine, bromine, iodine, benzeneselenenyl chloride, and benzenesulphenyl chloride has been studied.Under conditions of kinetic control both γ- and δ-lactones are formed, the δ lactone being predominant except in the case of bromine.The thermodynamic product distributions favored the δ-lactone exclusively.A general mechanistic scheme is proposed.